Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| PDXHCI002 | Degrasyn | 3.16 | 0.1139 | 0.39234 |
| PDXHCI002 | Degrasyn | 9.992797406 | -0.4741 | 0.57928 |
| PDXHCI002 | Degrasyn | 31.6 | -0.5716 | 0.64273 |
| PDXHCI002 | Degrasyn | 50.0 | -0.6095 | 0.39808 |
| PDXHCI002 | Sepantronium | 0.009992797 | 1.0923 | -0.00421 |
| PDXHCI002 | Sepantronium | 0.0316 | 0.8655 | 0.03493 |
| PDXHCI002 | Sepantronium | 0.099927974 | 0.3744 | 0.15377 |
| PDXHCI002 | Sepantronium | 0.316 | -0.1838 | 0.30961 |
| PDXHCI002 | Sepantronium | 0.999279741 | -0.3216 | 0.41818 |
| PDXHCI002 | Sepantronium | 3.16 | -0.4176 | 0.47038 |
| PDXHCI002 | Sepantronium | 9.992797406 | -0.4540 | 0.56650 |
| PDXHCI002 | Sepantronium | 31.6 | -0.5056 | 0.61199 |
| PDXHCI002 | Sepantronium | 50.0 | -0.5798 | 0.42177 |
| PDXHCI002 | z-VAE(OMe)-fmk | 0.009992797 | 1.0151 | -0.00058 |
| PDXHCI002 | z-VAE(OMe)-fmk | 0.0316 | 0.8623 | -0.00363 |
| PDXHCI002 | z-VAE(OMe)-fmk | 0.099927974 | 0.9831 | 0.01021 |
| PDXHCI002 | z-VAE(OMe)-fmk | 0.316 | 0.9907 | -0.00311 |
| PDXHCI002 | z-VAE(OMe)-fmk | 0.999279741 | 0.8781 | 0.01358 |
| PDXHCI002 | z-VAE(OMe)-fmk | 3.16 | 0.9944 | 0.00661 |
| PDXHCI002 | z-VAE(OMe)-fmk | 9.992797406 | 0.9039 | 0.01151 |
| PDXHCI002 | z-VAE(OMe)-fmk | 31.6 | 0.9454 | 0.01215 |
| PDXHCI002 | z-VAE(OMe)-fmk | 50.0 | 0.9278 | -0.01517 |
| SK-BR-3 | 1247825-37-1 | 0.009992797 | 0.9494 | -0.00090 |
| SK-BR-3 | 1247825-37-1 | 0.0316 | 0.9846 | 0.00264 |
| SK-BR-3 | 1247825-37-1 | 0.099927974 | 0.8776 | 0.00860 |