Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20344)

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Cell Small Molecule Primary Target Pathway GR50 GRmax GR_AOC Death_AUC GR Hill Coefficient GEC50 GR r2
MCF 10A Taxol
Chemo
Chemotherapy
0.0026843
 -0.1256 0.7023 0.2576 1.8234
0.003018
0.9967
HCC1954 Taxol
Chemo
Chemotherapy
0.0024667
 -0.3961 0.8347 0.4142 1.6514
0.0034177
0.98666
HCC1428 Doxorubicin
Chemo
Chemotherapy
0.0047408
 -0.7396 0.8955 0.2242 0.5182
0.029971
0.95944
HCC1428 Cisplatin
Chemo
Chemotherapy
0.91164
 0.1223 0.2655 0.0096 1.2004
0.80529
0.9803
HCC1806 Taxol
Chemo
Chemotherapy
0.0014225
 -0.2113 0.8398 0.3493 2.1569
0.0016621
0.96243
MCF 10A Cisplatin
Chemo
Chemotherapy
4.2937
 0.3794 0.0952 0.0149 2.1287
2.4561
0.99519
MDA-MB-361 Taxol
Chemo
Chemotherapy
0.0031082
 -0.6090 0.9738 0.2561 2.5508
0.0042111
0.9201
HCC1419 Cisplatin
Chemo
Chemotherapy
1.7988
 0.0949 0.2293 0.0086 1.0769
2.0814
0.93793
PDX1328 Cisplatin
Chemo
Chemotherapy
0.77968
 -0.4217 0.3154 0.0259 1.3251
1.2886
0.9879
MDA-MB-231 Taxol
Chemo
Chemotherapy
0.0023185
 -0.1204 0.7021 0.2576 1.1720
0.0026636
0.96432
MDA-MB-157 Doxorubicin
Chemo
Chemotherapy
0.0032329
 -0.7766 0.9661 0.1885 0.9535
0.006701
0.93404
MDA-MB-436 Cisplatin
Chemo
Chemotherapy
0.4173
 -0.0204 0.3606 0.0365 1.2366
0.44452
0.99287
HCC1395 Cisplatin
Chemo
Chemotherapy
0.49099
 -0.2215 0.3857 0.0943 0.9090
0.84369
0.97444
MDA-MB-231 Doxorubicin
Chemo
Chemotherapy
0.0050428
 -0.4864 0.8179 0.2092 1.0560
0.0077676
0.95921
MDA-MB-231 Cisplatin
Chemo
Chemotherapy
2.415
 0.2721 0.1500 0.0084 1.6944
1.6486
0.99899
HCC70 Cisplatin
Chemo
Chemotherapy
1.3073
 -0.6832 0.2650 0.0820 1.3165
3.0116
0.99076
HCC38 Taxol
Chemo
Chemotherapy
0.0014659
 -0.3078 0.8432 0.2758 2.3201
0.0017274
0.99328
CAMA-1 Cisplatin
Chemo
Chemotherapy
0.91281
 -0.0042 0.3350 0.0351 0.4780
9.0889
0.95264
CAMA-1 Doxorubicin
Chemo
Chemotherapy
0.0074655
 -0.6517 0.8426 0.2593 0.7583
0.020458
0.96039
HCC38 Doxorubicin
Chemo
Chemotherapy
0.0095452
 -0.4061 0.7803 0.2872 1.4810
0.01343
0.99228
HCC38 Cisplatin
Chemo
Chemotherapy
0.99272
 -0.1031 0.2567 0.1098 1.4350
1.1794
0.99675
HCC1500 Taxol
Chemo
Chemotherapy
0.0038131
 -0.0589 0.6182 0.1433 1.8138
0.0038924
0.96247
HCC1395 Doxorubicin
Chemo
Chemotherapy
0.01793
 -0.4166 0.6370 0.1543 1.1158
0.025315
0.96347
CAMA-1 Taxol
Chemo
Chemotherapy
0.0022699
 -0.4944 0.9525 0.3547 2.4920
0.0029769
0.99478
HCC1500 Doxorubicin
Chemo
Chemotherapy
0.016258
 -0.7134 0.7518 0.1833 0.7212
0.058468
0.98572