Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
|---|---|---|---|---|---|---|
| SUM1315MO2 | ABT-737 | 3.1623 | Bcl2/XL | Misc | 0.7434 | 0.07861 |
| BT-20 | Alpelisib | 3.1623 | PI3Ka | PI3K/mTOR | 0.3868 | 0.10646 |
| HCC1954 | Vorinostat | 3.1623 | HDAC | Misc | 0.1908 | 0.24286 |
| MDA-MB-453 | Vorinostat | 3.1623 | HDAC | Misc | -0.4986 | 0.53830 |
| CAL-85-1 | Cabozantinib | 3.1623 | VEGFR2/MET | RTK | 0.7204 | 0.02854 |
| MDA-MB-157 | Cisplatin | 3.1623 | Chemo | Chemotherapy | 0.6919 | 0.01417 |
| SUM1315MO2 | Saracatinib | 3.1623 | SRC | MAPK/nRTK | 0.3317 | 0.10537 |
| T47D | TGX221 | 3.1623 | PI3Kb | PI3K/mTOR | 0.9245 | -0.00077 |
| HCC1419 | Ipatasertib | 3.1623 | AKT | PI3K/mTOR | 0.6479 | 0.00467 |
| BT-20 | TGX221 | 3.1623 | PI3Kb | PI3K/mTOR | 1.0471 | -0.01046 |