Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1806 TGX221
0.01
PI3Kb
PI3K/mTOR
 1.0814 -0.00181
HCC1806 TGX221
0.031623
PI3Kb
PI3K/mTOR
 1.0165 0.00477
HCC1806 TGX221
0.1
PI3Kb
PI3K/mTOR
 0.9502 0.00647
HCC1806 TGX221
0.31623
PI3Kb
PI3K/mTOR
 0.9951 0.00969
HCC1806 TGX221
1.0
PI3Kb
PI3K/mTOR
 1.0527 0.00379
HCC1806 TGX221
3.1623
PI3Kb
PI3K/mTOR
 1.0207 -0.00297
HCC1806 TGX221
10.0
PI3Kb
PI3K/mTOR
 0.9819 0.00736
HCC1806 Torin2
0.0001
mTOR/ATM/ATR
PI3K/mTOR
 1.0343 -0.00199
HCC1806 Torin2
0.00031623
mTOR/ATM/ATR
PI3K/mTOR
 0.9399 0.00840
HCC1806 Torin2
0.001
mTOR/ATM/ATR
PI3K/mTOR
 0.9960 -0.00157
HCC1806 Torin2
0.0031623
mTOR/ATM/ATR
PI3K/mTOR
 1.0012 -0.00204
HCC1806 Torin2
0.01
mTOR/ATM/ATR
PI3K/mTOR
 0.7502 0.01638
HCC1806 Torin2
0.031623
mTOR/ATM/ATR
PI3K/mTOR
 0.5414 0.05114
HCC1806 Torin2
0.1
mTOR/ATM/ATR
PI3K/mTOR
 0.1989 0.16033
HCC1806 Torin2
0.31623
mTOR/ATM/ATR
PI3K/mTOR
 0.0241 0.27795
HCC1806 Torin2
1.0
mTOR/ATM/ATR
PI3K/mTOR
 -0.1402 0.39541
HCC1806 Everolimus
0.001
mTOR1
PI3K/mTOR
 0.7828 0.01087
HCC1806 Everolimus
0.0031623
mTOR1
PI3K/mTOR
 0.8007 0.00711
HCC1806 Everolimus
0.01
mTOR1
PI3K/mTOR
 0.7914 0.00620
HCC1806 Everolimus
0.031623
mTOR1
PI3K/mTOR
 0.8058 -0.00145
HCC1806 Everolimus
0.1
mTOR1
PI3K/mTOR
 0.7066 0.00263
HCC1806 Everolimus
0.31623
mTOR1
PI3K/mTOR
 0.8440 -0.00381
HCC1806 Everolimus
1.0
mTOR1
PI3K/mTOR
 0.8179 -0.00356
HCC1806 Everolimus
3.1623
mTOR1
PI3K/mTOR
 0.8168 -0.00407
HCC1806 Everolimus
10.0
mTOR1
PI3K/mTOR
 0.8953 -0.01004