Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1428 Luminespib
0.01
HSP90
Misc
 -0.0037 0.16617
HCC1428 Luminespib
0.031623
HSP90
Misc
 0.0003 0.17388
HCC1428 Luminespib
0.1
HSP90
Misc
 -0.0109 0.15229
HCC1428 Luminespib
0.31623
HSP90
Misc
 -0.0043 0.15016
HCC1428 Luminespib
1.0
HSP90
Misc
 -0.0001 0.17350
HCC1428 A-1210477
0.001
Mcl-1
Misc
 1.0724 0.00692
HCC1428 A-1210477
0.0031623
Mcl-1
Misc
 1.0518 -0.00065
HCC1428 A-1210477
0.01
Mcl-1
Misc
 1.0263 -0.00143
HCC1428 A-1210477
0.031623
Mcl-1
Misc
 1.1316 0.00303
HCC1428 A-1210477
0.1
Mcl-1
Misc
 1.0366 0.00095
HCC1428 A-1210477
0.31623
Mcl-1
Misc
 1.0470 -0.00012
HCC1428 A-1210477
1.0
Mcl-1
Misc
 1.0377 -0.00012
HCC1428 A-1210477
3.1623
Mcl-1
Misc
 0.9850 -0.00472
HCC1428 A-1210477
10.0
Mcl-1
Misc
 0.8155 0.01947
HCC1428 Olaparib
0.001
PARP
Misc
 1.0474 -0.00474
HCC1428 Olaparib
0.0031623
PARP
Misc
 0.9829 0.00265
HCC1428 Olaparib
0.01
PARP
Misc
 0.8869 0.00682
HCC1428 Olaparib
0.031623
PARP
Misc
 0.9432 -0.00105
HCC1428 Olaparib
0.1
PARP
Misc
 0.8295 0.00315
HCC1428 Olaparib
0.31623
PARP
Misc
 0.6084 0.01056
HCC1428 Olaparib
1.0
PARP
Misc
 0.3798 0.01088
HCC1428 Olaparib
3.1623
PARP
Misc
 0.2035 0.02022
HCC1428 Olaparib
10.0
PARP
Misc
 0.1185 0.03197
HCC1428 Bleomycin
0.0010833
Radiation
Misc
 1.0176 -0.00505
HCC1428 Bleomycin
0.0033333
Radiation
Misc
 0.9136 0.00159