Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
CAL-120 Olaparib
0.031623
PARP
Misc
 0.9709 0.00020
CAL-120 Olaparib
0.1
PARP
Misc
 0.8916 0.00467
CAL-120 Olaparib
0.31623
PARP
Misc
 0.8846 0.00592
CAL-120 Olaparib
1.0
PARP
Misc
 0.8328 0.01226
CAL-120 Olaparib
3.1623
PARP
Misc
 0.6691 0.02908
CAL-120 Olaparib
10.0
PARP
Misc
 0.2688 0.10465
CAL-120 Bleomycin
0.0010833
Radiation
Misc
 0.9792 0.00323
CAL-120 Bleomycin
0.0033333
Radiation
Misc
 0.9867 0.00017
CAL-120 Bleomycin
0.01
Radiation
Misc
 0.9882 0.00323
CAL-120 Bleomycin
0.031667
Radiation
Misc
 0.9509 0.00918
CAL-120 Bleomycin
0.1
Radiation
Misc
 0.9281 0.01319
CAL-120 Bleomycin
0.31623
Radiation
Misc
 0.7999 0.03885
CAL-120 Bleomycin
1.0
Radiation
Misc
 0.6486 0.09415
CAL-120 Bleomycin
3.1623
Radiation
Misc
 0.3227 0.21394
CAL-120 Bleomycin
10.0
Radiation
Misc
 0.0886 0.22759
CAL-120 Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9765 -0.00081
CAL-120 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.0117 -0.00307
CAL-120 Ipatasertib
0.01
AKT
PI3K/mTOR
 0.9835 -0.00295
CAL-120 Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.9413 -0.00498
CAL-120 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.8875 -0.00261
CAL-120 Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.8246 -0.00744
CAL-120 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.7753 -0.00495
CAL-120 Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.7502 -0.00680
CAL-120 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.5993 0.00381
CAL-120 Alpelisib
0.001
PI3Ka
PI3K/mTOR
 0.9857 0.00461