Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
---|---|---|---|---|---|---|
CAL-120 | Doxorubicin | 0.0031623 | Chemo | Chemotherapy | 0.8587 | 0.02834 |
CAL-120 | Doxorubicin | 0.01 | Chemo | Chemotherapy | 0.4668 | 0.21414 |
CAL-120 | Doxorubicin | 0.031623 | Chemo | Chemotherapy | 0.0531 | 0.17039 |
CAL-120 | Doxorubicin | 0.1 | Chemo | Chemotherapy | -0.0470 | 0.10564 |
CAL-120 | Doxorubicin | 0.31623 | Chemo | Chemotherapy | -0.0962 | 0.16728 |
CAL-120 | Doxorubicin | 1.0 | Chemo | Chemotherapy | -0.1395 | 0.20579 |
CAL-120 | Doxorubicin | 3.1623 | Chemo | Chemotherapy | -0.2475 | 0.32662 |
CAL-120 | Taxol | 0.0001 | Chemo | Chemotherapy | 0.7833 | 0.06358 |
CAL-120 | Taxol | 0.00031623 | Chemo | Chemotherapy | 1.0000 | 0.00405 |
CAL-120 | Taxol | 0.001 | Chemo | Chemotherapy | 0.9612 | 0.04460 |
CAL-120 | Taxol | 0.0031623 | Chemo | Chemotherapy | 0.4234 | 0.22384 |
CAL-120 | Taxol | 0.01 | Chemo | Chemotherapy | -0.1171 | 0.46389 |
CAL-120 | Taxol | 0.031623 | Chemo | Chemotherapy | -0.1563 | 0.49109 |
CAL-120 | Taxol | 0.1 | Chemo | Chemotherapy | -0.1942 | 0.50540 |
CAL-120 | Taxol | 0.31623 | Chemo | Chemotherapy | -0.1801 | 0.49485 |
CAL-120 | Taxol | 1.0 | Chemo | Chemotherapy | -0.1987 | 0.50244 |
CAL-120 | Topotecan | 0.0010833 | Topo I | Chemotherapy | 0.9209 | 0.00418 |
CAL-120 | Topotecan | 0.0033333 | Topo I | Chemotherapy | 0.7734 | 0.01420 |
CAL-120 | Topotecan | 0.01 | Topo I | Chemotherapy | 0.3863 | 0.09321 |
CAL-120 | Topotecan | 0.031667 | Topo I | Chemotherapy | -0.0229 | 0.19841 |
CAL-120 | Topotecan | 0.1 | Topo I | Chemotherapy | -0.0758 | 0.21304 |
CAL-120 | Topotecan | 0.31623 | Topo I | Chemotherapy | -0.1147 | 0.27524 |
CAL-120 | Topotecan | 1.0 | Topo I | Chemotherapy | -0.1879 | 0.39253 |
CAL-120 | Topotecan | 3.1623 | Topo I | Chemotherapy | -0.3364 | 0.58074 |
CAL-120 | Topotecan | 10.0 | Topo I | Chemotherapy | -0.2921 | 0.52917 |