Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
CAL-120 Doxorubicin
0.0031623
Chemo
Chemotherapy
0.8587 0.02834
CAL-120 Doxorubicin
0.01
Chemo
Chemotherapy
0.4668 0.21414
CAL-120 Doxorubicin
0.031623
Chemo
Chemotherapy
0.0531 0.17039
CAL-120 Doxorubicin
0.1
Chemo
Chemotherapy
-0.0470 0.10564
CAL-120 Doxorubicin
0.31623
Chemo
Chemotherapy
-0.0962 0.16728
CAL-120 Doxorubicin
1.0
Chemo
Chemotherapy
-0.1395 0.20579
CAL-120 Doxorubicin
3.1623
Chemo
Chemotherapy
-0.2475 0.32662
CAL-120 Taxol
0.0001
Chemo
Chemotherapy
0.7833 0.06358
CAL-120 Taxol
0.00031623
Chemo
Chemotherapy
1.0000 0.00405
CAL-120 Taxol
0.001
Chemo
Chemotherapy
0.9612 0.04460
CAL-120 Taxol
0.0031623
Chemo
Chemotherapy
0.4234 0.22384
CAL-120 Taxol
0.01
Chemo
Chemotherapy
-0.1171 0.46389
CAL-120 Taxol
0.031623
Chemo
Chemotherapy
-0.1563 0.49109
CAL-120 Taxol
0.1
Chemo
Chemotherapy
-0.1942 0.50540
CAL-120 Taxol
0.31623
Chemo
Chemotherapy
-0.1801 0.49485
CAL-120 Taxol
1.0
Chemo
Chemotherapy
-0.1987 0.50244
CAL-120 Topotecan
0.0010833
Topo I
Chemotherapy
0.9209 0.00418
CAL-120 Topotecan
0.0033333
Topo I
Chemotherapy
0.7734 0.01420
CAL-120 Topotecan
0.01
Topo I
Chemotherapy
0.3863 0.09321
CAL-120 Topotecan
0.031667
Topo I
Chemotherapy
-0.0229 0.19841
CAL-120 Topotecan
0.1
Topo I
Chemotherapy
-0.0758 0.21304
CAL-120 Topotecan
0.31623
Topo I
Chemotherapy
-0.1147 0.27524
CAL-120 Topotecan
1.0
Topo I
Chemotherapy
-0.1879 0.39253
CAL-120 Topotecan
3.1623
Topo I
Chemotherapy
-0.3364 0.58074
CAL-120 Topotecan
10.0
Topo I
Chemotherapy
-0.2921 0.52917