Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC70 Everolimus
0.31623
mTOR1
PI3K/mTOR
 0.5270 0.03892
HCC70 Everolimus
1.0
mTOR1
PI3K/mTOR
 0.4073 0.06231
HCC70 Everolimus
3.1623
mTOR1
PI3K/mTOR
 0.3753 0.05110
HCC70 Everolimus
10.0
mTOR1
PI3K/mTOR
 0.3727 0.08626
HCC70 INK-128
0.00031623
mTORC1/2
PI3K/mTOR
 1.0342 0.00258
HCC70 INK-128
0.001
mTORC1/2
PI3K/mTOR
 0.8592 0.01537
HCC70 INK-128
0.0031623
mTORC1/2
PI3K/mTOR
 0.6188 0.02965
HCC70 INK-128
0.01
mTORC1/2
PI3K/mTOR
 0.2712 0.07039
HCC70 INK-128
0.031623
mTORC1/2
PI3K/mTOR
 0.1000 0.09457
HCC70 INK-128
0.1
mTORC1/2
PI3K/mTOR
 0.0297 0.11496
HCC70 INK-128
0.31623
mTORC1/2
PI3K/mTOR
 0.0451 0.11779
HCC70 INK-128
1.0
mTORC1/2
PI3K/mTOR
 0.0203 0.14927
HCC70 INK-128
3.1623
mTORC1/2
PI3K/mTOR
 -0.1620 0.22663
HCC70 PF-4708671
0.001
p70S6K
PI3K/mTOR
 1.1190 0.00064
HCC70 PF-4708671
0.0031623
p70S6K
PI3K/mTOR
 1.1135 0.00979
HCC70 PF-4708671
0.01
p70S6K
PI3K/mTOR
 1.2821 0.00396
HCC70 PF-4708671
0.031623
p70S6K
PI3K/mTOR
 1.1194 0.00717
HCC70 PF-4708671
0.1
p70S6K
PI3K/mTOR
 1.0416 -0.00039
HCC70 PF-4708671
0.31623
p70S6K
PI3K/mTOR
 1.0235 0.00740
HCC70 PF-4708671
1.0
p70S6K
PI3K/mTOR
 0.9240 0.00333
HCC70 PF-4708671
3.1623
p70S6K
PI3K/mTOR
 1.0846 0.00021
HCC70 PF-4708671
10.0
p70S6K
PI3K/mTOR
 0.9348 -0.00038
HCC70 Buparlisib
0.001
pan PI3K
PI3K/mTOR
 1.1846 -0.00002
HCC70 Buparlisib
0.0031623
pan PI3K
PI3K/mTOR
 1.1236 -0.00476
HCC70 Buparlisib
0.01
pan PI3K
PI3K/mTOR
 1.1167 0.00318