Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
Hs 578T Vorinostat
0.001
HDAC
Misc
 1.0117 0.00084
BT-20 Vorinostat
3.1623
HDAC
Misc
 0.3234 0.21206
MDA-MB-231 Vorinostat
0.031623
HDAC
Misc
 0.9748 0.01298
MDA-MB-231 Vorinostat
0.01
HDAC
Misc
 0.9804 0.00616
MDA-MB-231 Vorinostat
0.001
HDAC
Misc
 0.9726 0.00502
BT-20 Vorinostat
1.0
HDAC
Misc
 0.7991 0.05872
BT-20 Vorinostat
0.031623
HDAC
Misc
 1.0906 0.00068
BT-20 Vorinostat
0.001
HDAC
Misc
 1.0736 -0.00774
BT-20 Vorinostat
0.0031623
HDAC
Misc
 1.0276 -0.00162
BT-20 Vorinostat
0.1
HDAC
Misc
 1.0164 0.00615
BT-20 Vorinostat
0.31623
HDAC
Misc
 0.9768 0.01830
CAL-85-1 Vorinostat
1.0
HDAC
Misc
 0.5456 0.03482
CAL-85-1 Vorinostat
3.1623
HDAC
Misc
 0.0776 0.08535
MDA-MB-157 Vorinostat
0.001
HDAC
Misc
 1.0639 -0.00273
MCF 10A Vorinostat
0.01
HDAC
Misc
 1.0097 0.00067
MCF 10A Vorinostat
0.001
HDAC
Misc
 1.0052 0.00132
HCC38 Vorinostat
3.1623
HDAC
Misc
 -0.0938 0.40719
Hs 578T Vorinostat
0.31623
HDAC
Misc
 0.9301 0.00606
MCF 10A Vorinostat
0.031623
HDAC
Misc
 0.9993 0.00181
Hs 578T Vorinostat
0.0031623
HDAC
Misc
 0.9668 -0.00319
MCF 10A Vorinostat
0.0031623
HDAC
Misc
 0.9971 0.00002
HCC38 Vorinostat
10.0
HDAC
Misc
 -0.2851 0.46435
Hs 578T Vorinostat
0.031623
HDAC
Misc
 1.0296 0.00131
PDXHCI002 Vorinostat
1.0
HDAC
Misc
 -0.2956 0.60310
PDXHCI002 Vorinostat
0.31623
HDAC
Misc
 0.5298 0.13858