Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
|---|---|---|---|---|---|---|
| CAL-85-1 | Cisplatin | 0.31623 | Chemo | Chemotherapy | 0.8406 | 0.02080 |
| CAL-85-1 | Cisplatin | 1.0 | Chemo | Chemotherapy | 0.5118 | 0.10269 |
| CAL-85-1 | Cisplatin | 3.1623 | Chemo | Chemotherapy | 0.1577 | 0.21163 |
| CAL-85-1 | Cisplatin | 10.0 | Chemo | Chemotherapy | 0.0180 | 0.28653 |
| CAL-85-1 | Doxorubicin | 0.00031623 | Chemo | Chemotherapy | 0.9838 | 0.01234 |
| CAL-85-1 | Doxorubicin | 0.001 | Chemo | Chemotherapy | 0.9229 | 0.00529 |
| CAL-85-1 | Doxorubicin | 0.0031623 | Chemo | Chemotherapy | 0.7513 | 0.03511 |
| CAL-85-1 | Doxorubicin | 0.01 | Chemo | Chemotherapy | 0.1770 | 0.20608 |
| CAL-85-1 | Doxorubicin | 0.031623 | Chemo | Chemotherapy | -0.0825 | 0.19838 |
| CAL-85-1 | Doxorubicin | 0.1 | Chemo | Chemotherapy | -0.1466 | 0.25896 |
| CAL-85-1 | Doxorubicin | 0.31623 | Chemo | Chemotherapy | -0.3313 | 0.43593 |
| CAL-85-1 | Doxorubicin | 1.0 | Chemo | Chemotherapy | -0.3783 | 0.43963 |
| CAL-85-1 | Doxorubicin | 3.1623 | Chemo | Chemotherapy | -0.3695 | 0.35199 |
| CAL-85-1 | Taxol | 0.0001 | Chemo | Chemotherapy | 0.6999 | 0.13601 |
| CAL-85-1 | Taxol | 0.00031623 | Chemo | Chemotherapy | 1.0218 | 0.00805 |
| CAL-85-1 | Taxol | 0.001 | Chemo | Chemotherapy | 0.9681 | 0.02217 |
| CAL-85-1 | Taxol | 0.0031623 | Chemo | Chemotherapy | 0.3714 | 0.20733 |
| CAL-85-1 | Taxol | 0.01 | Chemo | Chemotherapy | -0.1102 | 0.46808 |
| CAL-85-1 | Taxol | 0.031623 | Chemo | Chemotherapy | -0.1714 | 0.51136 |
| CAL-85-1 | Taxol | 0.1 | Chemo | Chemotherapy | -0.2884 | 0.55715 |
| CAL-85-1 | Taxol | 0.31623 | Chemo | Chemotherapy | -0.3464 | 0.54731 |
| CAL-85-1 | Taxol | 1.0 | Chemo | Chemotherapy | -0.2791 | 0.55869 |
| CAL-85-1 | Topotecan | 0.0010833 | Topo I | Chemotherapy | 0.8904 | 0.01434 |
| CAL-85-1 | Topotecan | 0.0033333 | Topo I | Chemotherapy | 0.9204 | 0.01512 |
| CAL-85-1 | Topotecan | 0.01 | Topo I | Chemotherapy | 0.6888 | 0.05244 |