Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
MCF 10A Saracatinib
0.31623
SRC
MAPK/nRTK
 0.9401 -0.00110
MCF 10A Saracatinib
1.0
SRC
MAPK/nRTK
 0.8827 0.00017
MCF 10A Saracatinib
3.1623
SRC
MAPK/nRTK
 0.6667 0.00620
MCF 10A Saracatinib
10.0
SRC
MAPK/nRTK
 0.1485 0.05781
MCF 10A ABT-737
0.001
Bcl2/XL
Misc
 1.0007 0.00070
MCF 10A ABT-737
0.0031623
Bcl2/XL
Misc
 1.0099 0.00166
MCF 10A ABT-737
0.01
Bcl2/XL
Misc
 1.0074 0.00127
MCF 10A ABT-737
0.031623
Bcl2/XL
Misc
 1.0092 0.00213
MCF 10A ABT-737
0.1
Bcl2/XL
Misc
 1.0115 0.00613
MCF 10A ABT-737
0.31623
Bcl2/XL
Misc
 1.0072 0.00618
MCF 10A ABT-737
1.0
Bcl2/XL
Misc
 1.0022 0.00960
MCF 10A ABT-737
3.1623
Bcl2/XL
Misc
 0.9604 0.01007
MCF 10A ABT-737
10.0
Bcl2/XL
Misc
 0.8170 0.01207
MCF 10A Vorinostat
0.001
HDAC
Misc
 1.0052 0.00132
MCF 10A Vorinostat
0.0031623
HDAC
Misc
 0.9971 0.00002
MCF 10A Vorinostat
0.01
HDAC
Misc
 1.0097 0.00067
MCF 10A Vorinostat
0.031623
HDAC
Misc
 0.9993 0.00181
MCF 10A Vorinostat
0.1
HDAC
Misc
 0.9822 0.00019
MCF 10A Vorinostat
0.31623
HDAC
Misc
 0.9417 -0.00164
MCF 10A Vorinostat
1.0
HDAC
Misc
 0.7807 -0.00565
MCF 10A Vorinostat
3.1623
HDAC
Misc
 0.4182 0.00189
MCF 10A Vorinostat
10.0
HDAC
Misc
 0.0566 0.06002
MCF 10A Luminespib
0.0001
HSP90
Misc
 0.9989 0.00064
MCF 10A Luminespib
0.00031623
HSP90
Misc
 0.9986 -0.00107
MCF 10A Luminespib
0.001
HSP90
Misc
 0.9978 -0.00178