Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1806 INK-128
0.00031623
mTORC1/2
PI3K/mTOR
0.8966 0.00900
HCC1806 INK-128
0.001
mTORC1/2
PI3K/mTOR
0.9546 0.00204
HCC1806 INK-128
0.0031623
mTORC1/2
PI3K/mTOR
0.8982 0.00402
HCC1806 INK-128
0.01
mTORC1/2
PI3K/mTOR
0.7903 -0.00011
HCC1806 INK-128
0.031623
mTORC1/2
PI3K/mTOR
0.5319 0.03933
HCC1806 INK-128
0.1
mTORC1/2
PI3K/mTOR
0.4206 0.04042
HCC1806 INK-128
0.31623
mTORC1/2
PI3K/mTOR
0.3706 0.06159
HCC1806 INK-128
1.0
mTORC1/2
PI3K/mTOR
0.3388 0.06069
HCC1806 INK-128
3.1623
mTORC1/2
PI3K/mTOR
0.2620 0.10078
HCC1806 PF-4708671
0.001
p70S6K
PI3K/mTOR
1.0152 0.00592
HCC1806 PF-4708671
0.0031623
p70S6K
PI3K/mTOR
1.0299 0.00621
HCC1806 PF-4708671
0.01
p70S6K
PI3K/mTOR
0.9556 0.00302
HCC1806 PF-4708671
0.031623
p70S6K
PI3K/mTOR
1.0289 0.00535
HCC1806 PF-4708671
0.1
p70S6K
PI3K/mTOR
1.0369 -0.00429
HCC1806 PF-4708671
0.31623
p70S6K
PI3K/mTOR
1.0125 0.00535
HCC1806 PF-4708671
1.0
p70S6K
PI3K/mTOR
1.0192 -0.00999
HCC1806 PF-4708671
3.1623
p70S6K
PI3K/mTOR
1.1503 -0.01604
HCC1806 PF-4708671
10.0
p70S6K
PI3K/mTOR
1.2045 -0.02488
HCC1806 Buparlisib
0.001
pan PI3K
PI3K/mTOR
0.9469 0.00201
HCC1806 Buparlisib
0.0031623
pan PI3K
PI3K/mTOR
0.9890 0.00172
HCC1806 Buparlisib
0.01
pan PI3K
PI3K/mTOR
1.0201 0.00194
HCC1806 Buparlisib
0.031623
pan PI3K
PI3K/mTOR
1.0031 0.00148
HCC1806 Buparlisib
0.1
pan PI3K
PI3K/mTOR
0.9540 0.00375
HCC1806 Buparlisib
0.31623
pan PI3K
PI3K/mTOR
0.8857 0.00696
HCC1806 Buparlisib
1.0
pan PI3K
PI3K/mTOR
0.5541 0.08134