LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Palbociclib | 40.63 | 11.9 | 0.3215 | 0.6528 | 0.0417 | -0.0527 | 1.0490 | 0.3538 |
| MCF 10A-H2B-mCherry | Palbociclib | 42.33 | 11.9 | 0.2238 | 0.2 | 0.0225 | 0.1406 | 2.3287 | 0.3776 |
| MCF 10A-H2B-mCherry | Palbociclib | 44.03 | 11.9 | 0.2647 | 0.2203 | 0.0439 | 0.1171 | 1.2416 | 0.3844 |
| MCF 10A-H2B-mCherry | Palbociclib | 45.74 | 11.9 | 0.3222 | 0.2829 | 0.0596 | 0.0913 | 1.1227 | 0.3742 |
| MCF 10A-H2B-mCherry | Palbociclib | 47.45 | 11.9 | 0.4007 | 0.3571 | 0.0316 | 0.0791 | 1.1944 | 0.3387 |
| MCF 10A-H2B-mCherry | Palbociclib | 49.15 | 11.9 | 0.4833 | 0.4274 | -0.0214 | 0.0727 | 1.1331 | 0.3149 |
| MCF 10A-H2B-mCherry | Palbociclib | 50.86 | 11.9 | 0.6292 | 0.6556 | -0.0398 | -0.0226 | 0.9080 | 0.3102 |
| MCF 10A-H2B-mCherry | Palbociclib | 52.56 | 11.9 | 0.8479 | 0.9219 | -0.0364 | -0.0510 | 0.9614 | 0.2682 |
| MCF 10A-H2B-mCherry | Palbociclib | 54.25 | 11.9 | 1.4165 | 2.132 | -0.0451 | -0.2096 | 1.0540 | 0.2229 |
| MCF 10A-H2B-mCherry | Palbociclib | 55.97 | 11.9 | 1.7089 | 4.401 | -0.0551 | -0.4282 | 1.1480 | 0.2157 |
| MCF 10A-H2B-mCherry | Palbociclib | 57.67 | 11.9 | 1.7885 | 5.0733 | -0.1050 | -0.6168 | 1.0432 | 0.2239 |
| MCF 10A-H2B-mCherry | Palbociclib | 59.37 | 11.9 | 1.8094 | 7.7655 | -0.1104 | -0.8492 | 0.8174 | 0.2344 |
| MCF 10A-H2B-mCherry | Palbociclib | 61.08 | 11.9 | 2.1041 | 7.3693 | -0.0875 | -0.6827 | 1.3243 | 0.2108 |
| MCF 10A-H2B-mCherry | Palbociclib | 62.78 | 11.9 | 2.2517 | 3.462 | -0.1066 | -0.3708 | 1.4564 | 0.1912 |
| MCF 10A-H2B-mCherry | Palbociclib | 64.49 | 11.9 | 2.6977 | 3.6537 | -0.1909 | -0.3806 | 1.8197 | 0.1720 |
| MCF 10A-H2B-mCherry | Palbociclib | 66.19 | 11.9 | 2.9246 | 3.7993 | -0.2597 | -0.4149 | 2.1235 | 0.1823 |
| MCF 10A-H2B-mCherry | Palbociclib | 67.89 | 11.9 | 3.5863 | 5.6185 | -0.3169 | -0.7077 | 1.9844 | 0.1842 |
| MCF 10A-H2B-mCherry | Palbociclib | 69.60 | 11.9 | Inf | Inf | -0.4255 | -0.5524 | 1.2035 | 0.1809 |
| MCF 10A-H2B-mCherry | Palbociclib | 71.30 | 11.9 | Inf | Inf | -0.2922 | -0.3418 | 1.3773 | 0.1777 |
| MCF 10A-H2B-mCherry | Palbociclib | 73.49 | 11.9 | 3.8592 | 5.0055 | -0.9830 | -1.0000 | 4.3323 | 0.1600 |
| MCF 10A-H2B-mCherry | Palbociclib | 76.90 | 11.9 | 3.8753 | 4.8812 | -0.9978 | -1.0000 | 4.7782 | 0.1974 |
| MCF 10A-H2B-mCherry | Palbociclib | 80.31 | 11.9 | 3.7073 | 4.6207 | -0.9998 | -1.0000 | 5.0000 | 0.2973 |
| MCF 10A-H2B-mCherry | Palbociclib | 85.43 | 11.9 | Inf | Inf | -0.9917 | -0.9933 | 0.6160 | 0.5482 |
| MCF 10A-H2B-mCherry | Palbociclib | 85.43 | 12.0 | Inf | Inf | -0.9908 | -0.9912 | 0.5687 | 0.5120 |
| MCF 10A-H2B-mCherry | Palbociclib | 89.69 | 11.9 | Inf | Inf | -0.9796 | -0.9796 | 0.0000 | 0.6834 |