LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
---|---|---|---|---|---|---|---|---|---|
MCF 10A-H2B-mCherry | Vorinostat | 49.15 | 11.9 | 1.5433 | 1.8836 | -0.1670 | -0.2035 | 2.2201 | 0.2379 |
MCF 10A-H2B-mCherry | Vorinostat | 50.86 | 11.9 | 1.6427 | 2.2275 | -0.1772 | -0.2769 | 2.5033 | 0.2296 |
MCF 10A-H2B-mCherry | Vorinostat | 52.56 | 11.9 | 1.7015 | 2.2119 | -0.2009 | -0.2374 | 3.2129 | 0.2049 |
MCF 10A-H2B-mCherry | Vorinostat | 54.25 | 11.9 | 2.1006 | 2.42 | -0.1151 | -0.1804 | 2.8861 | 0.1820 |
MCF 10A-H2B-mCherry | Vorinostat | 55.97 | 11.9 | 2.1119 | 2.3545 | -0.1381 | -0.1723 | 3.1644 | 0.1856 |
MCF 10A-H2B-mCherry | Vorinostat | 57.67 | 11.9 | 2.3384 | 2.6827 | -0.0950 | -0.1809 | 2.9370 | 0.1725 |
MCF 10A-H2B-mCherry | Vorinostat | 59.37 | 11.9 | 2.1848 | 2.392 | -0.0905 | -0.1195 | 2.4477 | 0.1781 |
MCF 10A-H2B-mCherry | Vorinostat | 61.08 | 11.9 | 2.3764 | 2.5438 | -0.1126 | -0.0963 | 2.3719 | 0.1658 |
MCF 10A-H2B-mCherry | Vorinostat | 62.78 | 11.9 | 2.7049 | 2.7752 | -0.0004 | -0.0435 | 2.2956 | 0.1473 |
MCF 10A-H2B-mCherry | Vorinostat | 64.49 | 11.9 | 3.3049 | 3.3509 | -0.1239 | -0.0516 | 5.0000 | 0.1317 |
MCF 10A-H2B-mCherry | Vorinostat | 66.19 | 11.9 | 3.8965 | 3.9966 | -0.0930 | -0.0813 | 5.0000 | 0.1174 |
MCF 10A-H2B-mCherry | Vorinostat | 67.89 | 11.9 | 4.2349 | 4.3812 | -0.0390 | -0.0945 | 5.0000 | 0.1111 |
MCF 10A-H2B-mCherry | Vorinostat | 69.60 | 11.9 | 4.6605 | 4.5982 | 0.1156 | 0.0327 | 5.0000 | 0.1150 |
MCF 10A-H2B-mCherry | Vorinostat | 71.30 | 11.9 | Inf | Inf | 0.0118 | 0.0118 | 0.0000 | 0.1999 |
MCF 10A-H2B-mCherry | Vorinostat | 73.49 | 11.9 | Inf | Inf | -0.1017 | -0.1017 | 0.0000 | 0.3738 |
MCF 10A-H2B-mCherry | Vorinostat | 76.90 | 11.9 | Inf | Inf | -0.0732 | -0.0732 | 0.0000 | 0.4695 |
MCF 10A-H2B-mCherry | Vorinostat | 80.31 | 11.9 | Inf | Inf | -0.0761 | -0.0761 | 0.0000 | 0.6257 |
MCF 10A-H2B-mCherry | Vorinostat | 85.43 | 11.9 | Inf | Inf | 0.1827 | 0.1827 | 0.0000 | 0.6413 |
MCF 10A-H2B-mCherry | Vorinostat | 85.43 | 12.0 | Inf | Inf | 0.1293 | 0.1293 | 0.0000 | 0.6446 |
MCF 10A-H2B-mCherry | Vorinostat | 89.69 | 11.9 | Inf | Inf | 0.5920 | 0.5920 | 0.0000 | 0.6243 |