LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Alpelisib | 57.67 | 11.9 | Inf | Inf | 0.9066 | 0.8952 | 2.5000 | 0.0030 |
| MCF 10A-H2B-mCherry | Alpelisib | 59.37 | 11.9 | Inf | Inf | 0.9024 | 0.9024 | 0.0000 | 0.0172 |
| MCF 10A-H2B-mCherry | Alpelisib | 61.08 | 11.9 | Inf | Inf | 0.9110 | 0.9110 | 0.0000 | 0.0261 |
| MCF 10A-H2B-mCherry | Alpelisib | 62.78 | 11.9 | Inf | Inf | 0.9043 | 0.9043 | 0.0000 | 0.0082 |
| MCF 10A-H2B-mCherry | Alpelisib | 64.49 | 11.9 | Inf | Inf | 0.9987 | 0.9987 | 0.0000 | 0.0154 |
| MCF 10A-H2B-mCherry | Alpelisib | 66.19 | 11.9 | Inf | Inf | 0.9907 | 0.9907 | 0.0000 | 0.0377 |
| MCF 10A-H2B-mCherry | Alpelisib | 67.89 | 11.9 | Inf | Inf | 0.9130 | 0.9130 | 0.0000 | 0.0702 |
| MCF 10A-H2B-mCherry | Alpelisib | 69.60 | 11.9 | Inf | Inf | 0.8288 | 0.8288 | 0.0000 | 0.0594 |
| MCF 10A-H2B-mCherry | Alpelisib | 71.30 | 11.9 | Inf | Inf | 0.8057 | 0.8057 | 0.0000 | 0.0922 |
| MCF 10A-H2B-mCherry | Alpelisib | 73.49 | 11.9 | Inf | Inf | -0.1025 | -0.1025 | 0.0000 | 0.1541 |
| MCF 10A-H2B-mCherry | Alpelisib | 76.90 | 11.9 | Inf | Inf | -0.7311 | -0.7311 | 0.0000 | 0.2949 |
| MCF 10A-H2B-mCherry | Alpelisib | 80.31 | 11.9 | Inf | Inf | -0.9481 | -0.9481 | 0.0000 | 0.4247 |
| MCF 10A-H2B-mCherry | Alpelisib | 85.43 | 11.9 | Inf | Inf | -0.9874 | -0.9874 | 0.0000 | 0.8979 |
| MCF 10A-H2B-mCherry | Alpelisib | 85.43 | 12.0 | Inf | Inf | -0.9870 | -0.9870 | 0.0000 | 0.8881 |
| MCF 10A-H2B-mCherry | Alpelisib | 89.69 | 11.9 | Inf | Inf | -0.9954 | -0.9954 | 0.0000 | 1.0518 |
| MCF 10A-H2B-mCherry | Dasatinib | 15.08 | 11.9 | Inf | Inf | 0.1243 | -0.4244 | 0.2057 | 0.3924 |
| MCF 10A-H2B-mCherry | Dasatinib | 16.79 | 11.9 | Inf | Inf | 0.0863 | -0.4330 | 0.2049 | 0.4204 |
| MCF 10A-H2B-mCherry | Dasatinib | 18.49 | 11.9 | Inf | Inf | 0.0602 | -0.3489 | 0.2088 | 0.4503 |
| MCF 10A-H2B-mCherry | Dasatinib | 20.19 | 11.9 | 0.1745 | 0.6356 | 0.0392 | -0.1961 | 0.3732 | 0.4695 |
| MCF 10A-H2B-mCherry | Dasatinib | 21.90 | 11.9 | 0.1528 | 0.2547 | 0.0327 | -0.0888 | 0.5237 | 0.4742 |
| MCF 10A-H2B-mCherry | Dasatinib | 23.60 | 11.9 | 0.1781 | 0.1699 | 0.0396 | 0.0416 | 0.6705 | 0.4476 |
| MCF 10A-H2B-mCherry | Dasatinib | 25.30 | 11.9 | 0.1978 | 0.2226 | 0.0489 | 0.0284 | 0.7503 | 0.4393 |
| MCF 10A-H2B-mCherry | Dasatinib | 27.00 | 11.9 | 0.2252 | 0.2485 | 0.0269 | -0.0022 | 0.7064 | 0.4282 |
| MCF 10A-H2B-mCherry | Dasatinib | 28.71 | 11.9 | 0.258 | 0.3013 | 0.0083 | -0.0487 | 0.6118 | 0.4169 |
| MCF 10A-H2B-mCherry | Dasatinib | 30.41 | 11.9 | 0.3175 | 0.5926 | 0.0177 | -0.1331 | 0.5462 | 0.3989 |