LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 57.67 | 11.9 | 0.0016 | 0.0019 | -0.7476 | -0.6006 | 5.0000 | 0.9487 |
| MCF 10A-H2B-mCherry | Taxol | 59.37 | 11.9 | 0.0014 | 0.0017 | -0.5953 | -0.4995 | 4.0561 | 0.9069 |
| MCF 10A-H2B-mCherry | Taxol | 61.08 | 11.9 | 0.0014 | 0.0017 | -0.4542 | -0.5569 | 3.8012 | 0.9243 |
| MCF 10A-H2B-mCherry | Taxol | 62.78 | 11.9 | 0.0014 | 0.0017 | -0.6938 | -0.5140 | 4.2755 | 0.9151 |
| MCF 10A-H2B-mCherry | Taxol | 64.49 | 11.9 | 0.0016 | 0.0018 | -0.4233 | -0.4418 | 5.0000 | 0.8544 |
| MCF 10A-H2B-mCherry | Taxol | 66.19 | 11.9 | 0.0015 | 0.0018 | -0.7264 | -0.5641 | 5.0000 | 0.9534 |
| MCF 10A-H2B-mCherry | Taxol | 67.89 | 11.9 | 0.0011 | 0.0016 | -0.4845 | -0.5264 | 3.3721 | 0.9248 |
| MCF 10A-H2B-mCherry | Taxol | 69.60 | 11.9 | Inf | Inf | 0.6450 | 0.3071 | 2.4999 | 0.7524 |
| MCF 10A-H2B-mCherry | Taxol | 71.30 | 11.9 | 0.001 | 0.0014 | 0.1323 | -0.2625 | 3.2812 | 0.7769 |
| MCF 10A-H2B-mCherry | Taxol | 73.49 | 11.9 | Inf | Inf | -0.8372 | -0.6518 | 0.5709 | 1.0513 |
| MCF 10A-H2B-mCherry | Taxol | 76.90 | 11.9 | 0.0001 | 0.0003 | -0.9743 | -0.6652 | 0.7092 | 1.2470 |
| MCF 10A-H2B-mCherry | Taxol | 80.31 | 11.9 | 0.0 | 0.0002 | -1.0000 | -0.8852 | 0.6794 | 1.4491 |
| MCF 10A-H2B-mCherry | Taxol | 85.43 | 11.9 | Inf | Inf | -0.9909 | -0.8242 | 2.4551 | 1.5351 |
| MCF 10A-H2B-mCherry | Taxol | 85.43 | 12.0 | Inf | Inf | -0.9704 | -0.7957 | 2.4990 | 1.5206 |
| MCF 10A-H2B-mCherry | Taxol | 89.69 | 11.9 | 0.0001 | 0.0001 | -0.3321 | -0.7000 | 4.9958 | 1.5687 |
| MCF 10A-H2B-mCherry | Trametinib | 15.08 | 11.9 | Inf | Inf | 0.3411 | 0.3411 | 0.0000 | 0.3691 |
| MCF 10A-H2B-mCherry | Trametinib | 16.79 | 11.9 | Inf | Inf | 0.4137 | 0.4380 | 0.6914 | 0.4102 |
| MCF 10A-H2B-mCherry | Trametinib | 18.49 | 11.9 | Inf | Inf | 0.3116 | 0.3689 | 2.5000 | 0.4518 |
| MCF 10A-H2B-mCherry | Trametinib | 20.19 | 11.9 | 0.0012 | 0.0012 | 0.2434 | 0.3423 | 3.2856 | 0.5482 |
| MCF 10A-H2B-mCherry | Trametinib | 21.90 | 11.9 | 0.0013 | 0.0014 | 0.1822 | 0.2336 | 1.5224 | 0.6197 |
| MCF 10A-H2B-mCherry | Trametinib | 23.60 | 11.9 | 0.0013 | 0.0015 | 0.2225 | 0.1793 | 1.2585 | 0.6490 |
| MCF 10A-H2B-mCherry | Trametinib | 25.30 | 11.9 | 0.0017 | 0.0014 | 0.1022 | 0.1419 | 1.1785 | 0.6613 |
| MCF 10A-H2B-mCherry | Trametinib | 27.00 | 11.9 | 0.0019 | 0.0016 | 0.0473 | 0.1162 | 1.2836 | 0.6659 |
| MCF 10A-H2B-mCherry | Trametinib | 28.71 | 11.9 | 0.0019 | 0.0014 | 0.0832 | 0.1492 | 1.8509 | 0.6520 |
| MCF 10A-H2B-mCherry | Trametinib | 30.41 | 11.9 | 0.0023 | 0.0017 | 0.0870 | 0.1475 | 1.2021 | 0.6335 |