LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 34.19 | 11.8 | 0.001 | 0.0016 | -0.6566 | -0.5868 | 1.8654 | 0.9446 |
| MCF 10A-H2B-mCherry | Taxol | 36.16 | 11.8 | 0.0009 | 0.0015 | -0.6475 | -0.6132 | 1.7202 | 0.9852 |
| MCF 10A-H2B-mCherry | Taxol | 38.13 | 11.8 | 0.0009 | 0.0013 | -0.6497 | -0.5740 | 1.8740 | 0.9604 |
| MCF 10A-H2B-mCherry | Taxol | 40.10 | 11.8 | 0.0009 | 0.0013 | -0.7602 | -0.5270 | 2.1898 | 0.9227 |
| MCF 10A-H2B-mCherry | Taxol | 42.07 | 11.8 | 0.0008 | 0.0012 | -0.4692 | -0.4467 | 2.2248 | 0.8984 |
| MCF 10A-H2B-mCherry | Taxol | 44.04 | 11.8 | 0.0009 | 0.0011 | -0.2097 | -0.3273 | 2.5078 | 0.8390 |
| MCF 10A-H2B-mCherry | Taxol | 46.00 | 11.8 | 0.0008 | 0.0011 | -0.3949 | -0.4741 | 2.3963 | 0.9074 |
| MCF 10A-H2B-mCherry | Taxol | 47.98 | 11.8 | 0.0008 | 0.001 | -0.0628 | -0.3894 | 2.6434 | 0.8589 |
| MCF 10A-H2B-mCherry | Taxol | 49.95 | 11.8 | 0.0008 | 0.001 | 0.1595 | -0.2136 | 3.3339 | 0.7515 |
| MCF 10A-H2B-mCherry | Taxol | 51.92 | 11.8 | 0.0007 | 0.0009 | 0.3959 | -0.1137 | 3.3858 | 0.6843 |
| MCF 10A-H2B-mCherry | Taxol | 53.89 | 11.8 | Inf | Inf | 0.0000 | -0.1371 | 2.5000 | 0.6254 |
| MCF 10A-H2B-mCherry | Taxol | 56.36 | 12.8 | Inf | Inf | 0.0000 | -0.1380 | 2.5000 | 0.6797 |
| MCF 10A-H2B-mCherry | Taxol | 58.33 | 12.8 | Inf | Inf | -0.3263 | -0.3780 | 2.4987 | 0.6387 |
| MCF 10A-H2B-mCherry | Taxol | 60.30 | 12.8 | Inf | Inf | -0.3554 | -0.6653 | 2.5000 | 0.8293 |
| MCF 10A-H2B-mCherry | Taxol | 62.27 | 12.8 | Inf | Inf | -0.4494 | -0.7005 | 2.5000 | 0.8507 |
| MCF 10A-H2B-mCherry | Taxol | 64.24 | 12.8 | 0.0006 | 0.001 | -0.2726 | -0.5948 | 3.1044 | 0.9994 |
| MCF 10A-H2B-mCherry | Taxol | 66.21 | 12.8 | Inf | Inf | -0.4158 | -0.6719 | 2.5000 | 0.8786 |
| MCF 10A-H2B-mCherry | Taxol | 68.68 | 11.8 | 0.0011 | 0.0012 | -0.3052 | -0.4978 | 4.9979 | 0.9495 |
| MCF 10A-H2B-mCherry | Taxol | 70.65 | 11.8 | Inf | Inf | -0.6937 | -0.7735 | 2.5000 | 1.0129 |
| MCF 10A-H2B-mCherry | Taxol | 72.62 | 11.8 | 0.0011 | 0.0012 | -0.4139 | -0.4353 | 4.9999 | 0.9083 |
| MCF 10A-H2B-mCherry | Taxol | 74.59 | 11.8 | 0.0011 | 0.0012 | -0.1346 | -0.2979 | 4.9959 | 0.7808 |
| MCF 10A-H2B-mCherry | Taxol | 76.56 | 11.8 | 0.0011 | 0.0012 | -0.1940 | -0.3600 | 4.9956 | 0.8032 |
| MCF 10A-H2B-mCherry | Taxol | 78.53 | 11.8 | 0.0011 | 0.0012 | -0.4490 | -0.3760 | 4.9969 | 0.8513 |
| MCF 10A-H2B-mCherry | Taxol | 80.50 | 11.8 | 0.0009 | 0.0011 | -0.4560 | -0.4969 | 4.9979 | 0.8957 |
| MCF 10A-H2B-mCherry | Taxol | 82.47 | 11.8 | 0.0008 | 0.0008 | -0.4992 | -0.3263 | 5.0000 | 0.8223 |