LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Palbociclib | 60.30 | 12.8 | 5.3415 | 7.9799 | 0.1640 | -0.6574 | 3.2998 | 0.1583 |
| MCF 10A-H2B-mCherry | Palbociclib | 62.27 | 12.8 | Inf | Inf | 0.3703 | 0.3202 | 1.2436 | 0.0891 |
| MCF 10A-H2B-mCherry | Palbociclib | 64.24 | 12.8 | Inf | Inf | 0.2311 | 0.2111 | 2.5000 | 0.0711 |
| MCF 10A-H2B-mCherry | Palbociclib | 66.21 | 12.8 | Inf | Inf | 0.3784 | 0.3627 | 2.5000 | 0.0744 |
| MCF 10A-H2B-mCherry | Palbociclib | 68.68 | 11.8 | Inf | Inf | 0.2001 | 0.1415 | 2.5000 | 0.1170 |
| MCF 10A-H2B-mCherry | Palbociclib | 70.65 | 11.8 | Inf | Inf | 0.3868 | 0.2469 | 2.5000 | 0.0899 |
| MCF 10A-H2B-mCherry | Palbociclib | 72.62 | 11.8 | Inf | Inf | 0.1477 | 0.0937 | 2.5000 | 0.1111 |
| MCF 10A-H2B-mCherry | Palbociclib | 74.59 | 11.8 | 6.2258 | 8.3106 | -0.1752 | -0.7583 | 3.9365 | 0.1194 |
| MCF 10A-H2B-mCherry | Palbociclib | 76.56 | 11.8 | 7.1386 | 8.822 | -0.1401 | -0.8206 | 5.0000 | 0.0720 |
| MCF 10A-H2B-mCherry | Palbociclib | 78.53 | 11.8 | 6.8 | 7.9008 | -0.2637 | -0.6220 | 5.0000 | 0.0666 |
| MCF 10A-H2B-mCherry | Palbociclib | 80.50 | 11.8 | 6.7725 | 8.2243 | -0.3199 | -0.8211 | 5.0000 | 0.0725 |
| MCF 10A-H2B-mCherry | Palbociclib | 82.47 | 11.8 | 5.9596 | 7.8902 | -0.2712 | -0.8072 | 3.8956 | 0.0791 |
| MCF 10A-H2B-mCherry | Palbociclib | 84.44 | 11.8 | 7.8009 | 9.9225 | -0.0850 | -1.0000 | 5.0000 | 0.0239 |
| MCF 10A-H2B-mCherry | Palbociclib | 86.41 | 11.8 | Inf | Inf | 0.2113 | -0.0813 | 2.5000 | 0.0375 |
| MCF 10A-H2B-mCherry | Palbociclib | 88.39 | 11.8 | Inf | Inf | 0.1807 | 0.1415 | 2.5000 | 0.1081 |
| MCF 10A-H2B-mCherry | Taxol | 14.50 | 11.8 | 0.0054 | 0.0111 | -0.8917 | -0.8789 | 1.6037 | 0.7582 |
| MCF 10A-H2B-mCherry | Taxol | 16.47 | 11.8 | 0.0034 | 0.0083 | -0.9391 | -0.9437 | 1.3190 | 0.8401 |
| MCF 10A-H2B-mCherry | Taxol | 18.43 | 11.8 | 0.003 | 0.0066 | -0.9335 | -0.9228 | 1.4098 | 0.8755 |
| MCF 10A-H2B-mCherry | Taxol | 20.40 | 11.8 | 0.0027 | 0.0057 | -0.9423 | -0.9486 | 1.4238 | 0.9269 |
| MCF 10A-H2B-mCherry | Taxol | 22.37 | 11.8 | 0.0022 | 0.0052 | -0.9405 | -0.9510 | 1.3001 | 0.9473 |
| MCF 10A-H2B-mCherry | Taxol | 24.34 | 11.8 | 0.002 | 0.0046 | -0.9432 | -0.9101 | 1.2484 | 0.9442 |
| MCF 10A-H2B-mCherry | Taxol | 26.31 | 11.8 | 0.0016 | 0.0039 | -0.9101 | -0.9124 | 1.2276 | 0.9742 |
| MCF 10A-H2B-mCherry | Taxol | 28.28 | 11.8 | 0.0013 | 0.003 | -0.8701 | -0.8390 | 1.2391 | 0.9847 |
| MCF 10A-H2B-mCherry | Taxol | 30.24 | 11.8 | 0.0011 | 0.0024 | -0.8135 | -0.8348 | 1.2978 | 1.0177 |
| MCF 10A-H2B-mCherry | Taxol | 32.22 | 11.8 | 0.001 | 0.0019 | -0.8341 | -0.7201 | 1.5049 | 0.9893 |