LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 9 of 15: End-point dose-response metrics for biological replicate 3. - Dataset (ID:20317)
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Cell | Small Molecule | Time Point (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
---|---|---|---|---|---|---|---|---|
MCF 10A-H2B-mCherry | Palbociclib | 24 | Inf | Inf | 0.4526 | 0.4526 | 0.0000 | 0.3423 |
MCF 10A-H2B-mCherry | Trametinib | 12 | Inf | Inf | 0.5665 | 0.5665 | 0.0000 | 0.4216 |
MCF 10A-H2B-mCherry | Trametinib | 24 | Inf | Inf | 0.6669 | 0.6669 | 0.0000 | 0.3246 |
MCF 10A-H2B-mCherry | Trametinib | 36 | Inf | 0.0001 | 0.5993 | 0.6033 | 0.5390 | 0.3548 |
MCF 10A-H2B-mCherry | Trametinib | 48 | Inf | 0.0005 | 0.5447 | 0.5288 | 0.5177 | 0.3751 |
MCF 10A-H2B-mCherry | Vorinostat | 12 | Inf | Inf | 0.2827 | 0.2827 | 0.0000 | 0.5365 |