LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 9 of 15: End-point dose-response metrics for biological replicate 3. - Dataset (ID:20317)

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Cell Small Molecule Time Point (hr) GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC
MCF 10A-H2B-mCherry Alpelisib 12
Inf
Inf
0.6300 0.6300 0.0000 0.3905
MCF 10A-H2B-mCherry Alpelisib 24
Inf
Inf
0.6568 0.6568 0.0000 0.2481
MCF 10A-H2B-mCherry Alpelisib 36
Inf
Inf
0.6884 0.6884 0.0000 0.1933
MCF 10A-H2B-mCherry Alpelisib 48
Inf
Inf
0.7129 0.7129 0.0000 0.1620
MCF 10A-H2B-mCherry Alpelisib 60
Inf
Inf
0.7342 0.7342 0.0000 0.1444
MCF 10A-H2B-mCherry Alpelisib 72
Inf
Inf
0.7448 0.7448 0.0000 0.1385
MCF 10A-H2B-mCherry Alpelisib 84
Inf
Inf
0.7193 0.7193 0.0000 0.1230
MCF 10A-H2B-mCherry Dasatinib 12
Inf
Inf
0.3669 0.3669 0.0000 0.4736
MCF 10A-H2B-mCherry Dasatinib 24
Inf
Inf
0.3464 0.3464 0.0000 0.3987
MCF 10A-H2B-mCherry Dasatinib 36
1.8278
999.8676
0.3368 -0.9426 0.1681 0.3611
MCF 10A-H2B-mCherry Dasatinib 48
1.2987
299.0185
0.3294 -1.0000 0.2020 0.3592
MCF 10A-H2B-mCherry Dasatinib 60
1.0757
102.3859
0.1735 -1.0000 0.2412 0.3555
MCF 10A-H2B-mCherry Dasatinib 72
0.8672
64.7283
0.0603 -1.0000 0.2547 0.3653
MCF 10A-H2B-mCherry Dasatinib 84
0.5642
58.6317
-0.0543 -1.0000 0.2366 0.3960
MCF 10A-H2B-mCherry Etoposide 12
Inf
Inf
0.3340 0.3340 0.0000 0.4725
MCF 10A-H2B-mCherry Etoposide 24
2.0061
129.7291
0.2052 -1.0000 0.2635 0.3116
MCF 10A-H2B-mCherry Etoposide 36
1.5954
57.0859
0.1922 -1.0000 0.3071 0.3079
MCF 10A-H2B-mCherry Etoposide 48
1.1834
37.3253
0.1896 -1.0000 0.3183 0.3192
MCF 10A-H2B-mCherry Etoposide 60
0.847
16.3367
0.1412 -0.8621 0.3387 0.3416
MCF 10A-H2B-mCherry Etoposide 72
0.5612
1.2244
0.1419 -0.2015 0.4341 0.3610
MCF 10A-H2B-mCherry Etoposide 84
0.3533
0.6359
0.1344 -0.1515 0.4501 0.4060
MCF 10A-H2B-mCherry Neratinib 12
Inf
Inf
0.2348 0.2348 0.0000 0.4770
MCF 10A-H2B-mCherry Neratinib 24
0.0809
0.0088
0.2144 0.3494 0.5423 0.4143
MCF 10A-H2B-mCherry Neratinib 36
0.1462
0.1855
0.2073 -0.0474 0.3804 0.3953
MCF 10A-H2B-mCherry Neratinib 48
0.1895
4.5797
0.0307 -1.0000 0.3449 0.3845
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