LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 9 of 15: End-point dose-response metrics for biological replicate 3. - Dataset (ID:20317)
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| Cell | Small Molecule | Time Point (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Neratinib | 84 | 0.2629 | 2.4045 | -0.1966 | -1.0000 | 0.4964 | 0.3709 |
| MCF 10A-H2B-mCherry | Neratinib | 72 | 0.246 | 2.6692 | -0.1124 | -1.0000 | 0.4607 | 0.3588 |
| MCF 10A-H2B-mCherry | Taxol | 12 | 0.0017 | 2.6985 | 0.1492 | -1.0000 | 0.1490 | 0.5622 |
| MCF 10A-H2B-mCherry | Dasatinib | 48 | 1.2987 | 299.0185 | 0.3294 | -1.0000 | 0.2020 | 0.3592 |
| MCF 10A-H2B-mCherry | Palbociclib | 72 | 2.3133 | 319.7903 | 0.2433 | -1.0000 | 0.2229 | 0.3116 |
| MCF 10A-H2B-mCherry | Neratinib | 60 | 0.2207 | 3.2708 | -0.0756 | -1.0000 | 0.4075 | 0.3689 |
| MCF 10A-H2B-mCherry | Etoposide | 48 | 1.1834 | 37.3253 | 0.1896 | -1.0000 | 0.3183 | 0.3192 |
| MCF 10A-H2B-mCherry | Neratinib | 48 | 0.1895 | 4.5797 | 0.0307 | -1.0000 | 0.3449 | 0.3845 |
| MCF 10A-H2B-mCherry | Etoposide | 36 | 1.5954 | 57.0859 | 0.1922 | -1.0000 | 0.3071 | 0.3079 |
| MCF 10A-H2B-mCherry | Dasatinib | 84 | 0.5642 | 58.6317 | -0.0543 | -1.0000 | 0.2366 | 0.3960 |
| MCF 10A-H2B-mCherry | Dasatinib | 72 | 0.8672 | 64.7283 | 0.0603 | -1.0000 | 0.2547 | 0.3653 |
| MCF 10A-H2B-mCherry | Palbociclib | 60 | 2.6707 | 808.9177 | 0.3136 | -1.0000 | 0.1923 | 0.3179 |
| MCF 10A-H2B-mCherry | Dasatinib | 36 | 1.8278 | 999.8676 | 0.3368 | -0.9426 | 0.1681 | 0.3611 |
| MCF 10A-H2B-mCherry | Palbociclib | 36 | 8.2546 | 999.9626 | 0.4151 | -0.4519 | 0.1342 | 0.3252 |
| MCF 10A-H2B-mCherry | Palbociclib | 48 | 3.3346 | 999.9941 | 0.3630 | -0.7979 | 0.1673 | 0.3254 |
| MCF 10A-H2B-mCherry | Palbociclib | 12 | Inf | Inf | 0.5376 | 0.5376 | 0.0000 | 0.4133 |
| MCF 10A-H2B-mCherry | Alpelisib | 24 | Inf | Inf | 0.6568 | 0.6568 | 0.0000 | 0.2481 |
| MCF 10A-H2B-mCherry | Alpelisib | 36 | Inf | Inf | 0.6884 | 0.6884 | 0.0000 | 0.1933 |
| MCF 10A-H2B-mCherry | Alpelisib | 48 | Inf | Inf | 0.7129 | 0.7129 | 0.0000 | 0.1620 |
| MCF 10A-H2B-mCherry | Alpelisib | 60 | Inf | Inf | 0.7342 | 0.7342 | 0.0000 | 0.1444 |
| MCF 10A-H2B-mCherry | Alpelisib | 72 | Inf | Inf | 0.7448 | 0.7448 | 0.0000 | 0.1385 |
| MCF 10A-H2B-mCherry | Alpelisib | 84 | Inf | Inf | 0.7193 | 0.7193 | 0.0000 | 0.1230 |
| MCF 10A-H2B-mCherry | Dasatinib | 12 | Inf | Inf | 0.3669 | 0.3669 | 0.0000 | 0.4736 |
| MCF 10A-H2B-mCherry | Dasatinib | 24 | Inf | Inf | 0.3464 | 0.3464 | 0.0000 | 0.3987 |
| MCF 10A-H2B-mCherry | Etoposide | 12 | Inf | Inf | 0.3340 | 0.3340 | 0.0000 | 0.4725 |