LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 8 of 15: End-point dose-response metrics for biological replicate 2. - Dataset (ID:20316)
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| Cell | Small Molecule | Time Point (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 48 | 0.0009 | 0.0023 | -0.2904 | -0.4105 | 0.6256 | 0.7874 |
| MCF 10A-H2B-mCherry | Palbociclib | 48 | Inf | Inf | 0.3655 | 0.3655 | 0.0000 | 0.3443 |
| MCF 10A-H2B-mCherry | Alpelisib | 48 | Inf | Inf | 0.7368 | 0.7368 | 0.0000 | 0.2612 |
| MCF 10A-H2B-mCherry | Etoposide | 48 | 1.0407 | 79.7605 | 0.1715 | -1.0000 | 0.2532 | 0.3575 |
| MCF 10A-H2B-mCherry | Neratinib | 48 | 0.2009 | 11.344 | 0.1627 | -1.0000 | 0.2724 | 0.3954 |
| MCF 10A-H2B-mCherry | Vorinostat | 48 | 1.111 | 15.0584 | 0.1025 | -1.0000 | 0.4215 | 0.3662 |
| MCF 10A-H2B-mCherry | Dasatinib | 48 | Inf | Inf | 0.3357 | 0.3357 | 0.0000 | 0.3927 |
| MCF 10A-H2B-mCherry | Vorinostat | 72 | 1.435 | 21.5194 | 0.1227 | -1.0000 | 0.4057 | 0.3663 |
| MCF 10A-H2B-mCherry | Alpelisib | 72 | Inf | Inf | 0.8047 | 0.8047 | 0.0000 | 0.2441 |
| MCF 10A-H2B-mCherry | Palbociclib | 72 | Inf | Inf | 0.4218 | 0.4218 | 0.0000 | 0.3265 |
| MCF 10A-H2B-mCherry | Taxol | 72 | 0.0005 | 0.0011 | -0.2898 | -0.3494 | 0.6605 | 0.8468 |
| MCF 10A-H2B-mCherry | Trametinib | 72 | Inf | 0.0048 | 0.5610 | 0.5286 | 0.5137 | 0.2868 |
| MCF 10A-H2B-mCherry | Dasatinib | 72 | Inf | Inf | 0.2033 | 0.2033 | 0.0000 | 0.3884 |
| MCF 10A-H2B-mCherry | Etoposide | 72 | 0.4072 | 92.5315 | 0.1613 | -1.0000 | 0.2025 | 0.4334 |
| MCF 10A-H2B-mCherry | Neratinib | 72 | 0.2915 | 6.6939 | 0.0859 | -1.0000 | 0.3505 | 0.3727 |
| MCF 10A-H2B-mCherry | Vorinostat | 84 | 1.1734 | 54.8915 | 0.1209 | -1.0000 | 0.2857 | 0.4069 |
| MCF 10A-H2B-mCherry | Palbociclib | 84 | Inf | Inf | 0.3876 | 0.3876 | 0.0000 | 0.3349 |
| MCF 10A-H2B-mCherry | Etoposide | 84 | 0.1739 | 59.2726 | 0.1678 | -1.0000 | 0.1884 | 0.4947 |
| MCF 10A-H2B-mCherry | Neratinib | 84 | 0.2528 | 9.4484 | 0.0272 | -1.0000 | 0.3034 | 0.3990 |
| MCF 10A-H2B-mCherry | Taxol | 84 | 0.0003 | 0.0008 | -0.2773 | -0.3429 | 0.6241 | 0.8762 |
| MCF 10A-H2B-mCherry | Dasatinib | 84 | Inf | Inf | 0.1459 | 0.1459 | 0.0000 | 0.4301 |
| MCF 10A-H2B-mCherry | Trametinib | 84 | 6.7955 | 0.0263 | 0.5589 | 0.3962 | 0.2830 | 0.2816 |
| MCF 10A-H2B-mCherry | Alpelisib | 84 | Inf | Inf | 0.7374 | 0.7374 | 0.0000 | 0.3018 |