LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 8 of 15: End-point dose-response metrics for biological replicate 2. - Dataset (ID:20316)

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Cell Small Molecule Time Point (hr) GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC
MCF 10A-H2B-mCherry Dasatinib 36
Inf
Inf
 0.3554 0.3554 0.0000 0.4191
MCF 10A-H2B-mCherry Palbociclib 48
Inf
Inf
 0.3655 0.3655 0.0000 0.3443
MCF 10A-H2B-mCherry Neratinib 24
0.3492
0.0073
 0.4236 0.3755 0.3591 0.3870
MCF 10A-H2B-mCherry Palbociclib 84
Inf
Inf
 0.3876 0.3876 0.0000 0.3349
MCF 10A-H2B-mCherry Dasatinib 24
Inf
Inf
 0.3885 0.3885 0.0000 0.4429
MCF 10A-H2B-mCherry Palbociclib 24
Inf
Inf
 0.3926 0.3926 0.0000 0.3827
MCF 10A-H2B-mCherry Trametinib 84
6.7955
0.0263
 0.5589 0.3962 0.2830 0.2816
MCF 10A-H2B-mCherry Palbociclib 72
Inf
Inf
 0.4218 0.4218 0.0000 0.3265
MCF 10A-H2B-mCherry Vorinostat 12
Inf
Inf
 0.4594 0.4594 0.0000 0.4495
MCF 10A-H2B-mCherry Palbociclib 12
Inf
Inf
 0.4654 0.4654 0.0000 0.4378
MCF 10A-H2B-mCherry Neratinib 12
Inf
Inf
 0.4696 0.4696 0.0000 0.4345
MCF 10A-H2B-mCherry Dasatinib 12
Inf
Inf
 0.4761 0.4761 0.0000 0.4903
MCF 10A-H2B-mCherry Trametinib 72
Inf
0.0048
 0.5610 0.5286 0.5137 0.2868
MCF 10A-H2B-mCherry Alpelisib 12
Inf
Inf
 0.5346 0.5346 0.0000 0.4462
MCF 10A-H2B-mCherry Trametinib 12
Inf
Inf
 0.5691 0.5691 0.0000 0.4204
MCF 10A-H2B-mCherry Trametinib 48
Inf
0.0003
 0.5877 0.5701 0.3964 0.3405
MCF 10A-H2B-mCherry Alpelisib 24
Inf
Inf
 0.6050 0.6050 0.0000 0.3309
MCF 10A-H2B-mCherry Trametinib 36
Inf
Inf
 0.6568 0.6568 0.0000 0.3354
MCF 10A-H2B-mCherry Alpelisib 36
Inf
Inf
 0.7055 0.7055 0.0000 0.2829
MCF 10A-H2B-mCherry Trametinib 24
Inf
Inf
 0.7135 0.7135 0.0000 0.3120
MCF 10A-H2B-mCherry Alpelisib 48
Inf
Inf
 0.7368 0.7368 0.0000 0.2612
MCF 10A-H2B-mCherry Alpelisib 84
Inf
Inf
 0.7374 0.7374 0.0000 0.3018
MCF 10A-H2B-mCherry Alpelisib 72
Inf
Inf
 0.8047 0.8047 0.0000 0.2441