LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 8 of 15: End-point dose-response metrics for biological replicate 2. - Dataset (ID:20316)

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Cell Small Molecule Time Point (hr) GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC
MCF 10A-H2B-mCherry Dasatinib 48
Inf
Inf
 0.3357 0.3357 0.0000 0.3927
MCF 10A-H2B-mCherry Neratinib 48
0.2009
11.344
 0.1627 -1.0000 0.2724 0.3954
MCF 10A-H2B-mCherry Neratinib 84
0.2528
9.4484
 0.0272 -1.0000 0.3034 0.3990
MCF 10A-H2B-mCherry Vorinostat 84
1.1734
54.8915
 0.1209 -1.0000 0.2857 0.4069
MCF 10A-H2B-mCherry Neratinib 36
0.1336
0.0994
 0.2934 0.0455 0.3225 0.4123
MCF 10A-H2B-mCherry Dasatinib 36
Inf
Inf
 0.3554 0.3554 0.0000 0.4191
MCF 10A-H2B-mCherry Trametinib 12
Inf
Inf
 0.5691 0.5691 0.0000 0.4204
MCF 10A-H2B-mCherry Dasatinib 84
Inf
Inf
 0.1459 0.1459 0.0000 0.4301
MCF 10A-H2B-mCherry Etoposide 72
0.4072
92.5315
 0.1613 -1.0000 0.2025 0.4334
MCF 10A-H2B-mCherry Etoposide 12
Inf
Inf
 0.3263 0.3263 0.0000 0.4338
MCF 10A-H2B-mCherry Neratinib 12
Inf
Inf
 0.4696 0.4696 0.0000 0.4345
MCF 10A-H2B-mCherry Palbociclib 12
Inf
Inf
 0.4654 0.4654 0.0000 0.4378
MCF 10A-H2B-mCherry Dasatinib 24
Inf
Inf
 0.3885 0.3885 0.0000 0.4429
MCF 10A-H2B-mCherry Alpelisib 12
Inf
Inf
 0.5346 0.5346 0.0000 0.4462
MCF 10A-H2B-mCherry Vorinostat 12
Inf
Inf
 0.4594 0.4594 0.0000 0.4495
MCF 10A-H2B-mCherry Dasatinib 12
Inf
Inf
 0.4761 0.4761 0.0000 0.4903
MCF 10A-H2B-mCherry Etoposide 84
0.1739
59.2726
 0.1678 -1.0000 0.1884 0.4947
MCF 10A-H2B-mCherry Taxol 12
0.0005
0.0007
 0.2488 -0.0238 0.1003 0.5527
MCF 10A-H2B-mCherry Taxol 24
0.0018
0.0505
 -0.2179 -1.0000 0.3299 0.6617
MCF 10A-H2B-mCherry Taxol 36
0.0012
0.004
 -0.2810 -0.4927 0.5556 0.7513
MCF 10A-H2B-mCherry Taxol 48
0.0009
0.0023
 -0.2904 -0.4105 0.6256 0.7874
MCF 10A-H2B-mCherry Taxol 72
0.0005
0.0011
 -0.2898 -0.3494 0.6605 0.8468
MCF 10A-H2B-mCherry Taxol 84
0.0003
0.0008
 -0.2773 -0.3429 0.6241 0.8762