LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 1 | 63.60 | 56.33 | 988 | 7339 | 0.1295 | 0.4288 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 65.30 | 56.33 | 966 | 7570 | 0.1218 | 0.3954 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 67.00 | 56.33 | 931 | 7731 | 0.1139 | 0.3801 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 68.70 | 56.33 | 908 | 7933 | 0.1076 | 0.3611 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 70.50 | 56.33 | 907 | 7990 | 0.1063 | 0.3548 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 72.20 | 56.33 | 897 | 8053 | 0.1040 | 0.3482 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 73.90 | 56.33 | 923 | 8150 | 0.1058 | 0.3554 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 75.60 | 56.33 | 917 | 7992 | 0.1082 | 0.3595 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 77.30 | 56.33 | 907 | 8135 | 0.1048 | 0.3552 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 79.00 | 56.33 | 910 | 8048 | 0.1066 | 0.3566 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 80.70 | 56.33 | 918 | 7920 | 0.1096 | 0.3609 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 82.40 | 56.33 | 925 | 7810 | 0.1126 | 0.3640 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 84.10 | 56.33 | 922 | 7655 | 0.1158 | 0.3664 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 85.80 | 56.33 | 912 | 7583 | 0.1159 | 0.3654 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 87.50 | 56.33 | 914 | 7334 | 0.1216 | 0.3702 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 89.20 | 56.33 | 914 | 7229 | 0.1240 | 0.3704 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 90.90 | 56.33 | 912 | 7174 | 0.1249 | 0.3720 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 92.60 | 56.33 | 915 | 7065 | 0.1276 | 0.3737 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 94.30 | 56.33 | 895 | 6924 | 0.1285 | 0.3730 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 95.70 | 27.76 | 397 | 6712 | 0.0592 | 0.1920 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 2.30 | 56.33 | 293 | 255 | 1.1553 | 0.5900 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 4.00 | 56.33 | 339 | 303 | 1.1192 | 0.5596 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 5.70 | 56.33 | 382 | 342 | 1.1142 | 0.5400 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 7.40 | 56.33 | 421 | 385 | 1.0932 | 0.5276 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 9.10 | 56.33 | 460 | 424 | 1.0862 | 0.5362 |