LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 1 | 21.00 | 56.33 | 1015 | 1286 | 0.7779 | 0.8309 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 22.80 | 56.33 | 997 | 1460 | 0.6747 | 0.7874 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 24.50 | 56.33 | 1003 | 1615 | 0.6135 | 0.7649 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 26.20 | 56.33 | 1028 | 1764 | 0.5743 | 0.7442 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 27.90 | 56.33 | 1035 | 1907 | 0.5338 | 0.7324 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 29.60 | 56.33 | 1040 | 2050 | 0.4996 | 0.7187 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 31.30 | 56.33 | 1063 | 2241 | 0.4682 | 0.7044 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 33.00 | 56.33 | 1066 | 2479 | 0.4236 | 0.6813 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 34.70 | 56.33 | 1078 | 2720 | 0.3907 | 0.6650 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 36.40 | 56.33 | 1090 | 2958 | 0.3623 | 0.6508 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 38.10 | 56.33 | 1102 | 3168 | 0.3432 | 0.6450 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 39.80 | 56.33 | 1115 | 3393 | 0.3244 | 0.6356 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 41.50 | 56.33 | 1141 | 3667 | 0.3070 | 0.6278 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 43.20 | 56.33 | 1127 | 3942 | 0.2828 | 0.6143 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 44.90 | 56.33 | 1124 | 4212 | 0.2642 | 0.6028 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 46.60 | 56.33 | 1132 | 4538 | 0.2462 | 0.5911 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 48.30 | 56.33 | 1158 | 4875 | 0.2349 | 0.5851 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 50.00 | 56.33 | 1121 | 5234 | 0.2112 | 0.5669 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 51.70 | 56.33 | 1098 | 5553 | 0.1946 | 0.5519 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 53.40 | 56.33 | 1077 | 5809 | 0.1826 | 0.5416 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 55.10 | 56.33 | 1097 | 6087 | 0.1772 | 0.5373 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 56.80 | 56.33 | 1074 | 6354 | 0.1657 | 0.5255 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 58.50 | 56.33 | 1069 | 6599 | 0.1581 | 0.5145 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 60.20 | 56.33 | 1068 | 6852 | 0.1517 | 0.5078 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 61.90 | 56.33 | 1024 | 7075 | 0.1401 | 0.4815 |