LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 41.50 | 56.33 | 989 | 3667 | 0.2760 | 0.5717 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 43.20 | 56.33 | 998 | 3942 | 0.2590 | 0.5638 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 44.90 | 56.33 | 1015 | 4212 | 0.2460 | 0.5535 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 46.60 | 56.33 | 1003 | 4538 | 0.2267 | 0.5433 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 48.30 | 56.33 | 1029 | 4875 | 0.2162 | 0.5360 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 50.00 | 56.33 | 1052 | 5234 | 0.2052 | 0.5324 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 51.70 | 56.33 | 1056 | 5553 | 0.1940 | 0.5272 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 53.40 | 56.33 | 1046 | 5809 | 0.1836 | 0.5197 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 55.10 | 56.33 | 1071 | 6087 | 0.1796 | 0.5184 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 56.80 | 56.33 | 1065 | 6354 | 0.1720 | 0.5136 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 58.50 | 56.33 | 1089 | 6599 | 0.1699 | 0.5130 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 60.20 | 56.33 | 1104 | 6852 | 0.1665 | 0.5123 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 61.90 | 56.33 | 1106 | 7075 | 0.1621 | 0.5085 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 63.60 | 56.33 | 1103 | 7339 | 0.1555 | 0.5017 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 65.30 | 56.33 | 1090 | 7570 | 0.1489 | 0.4963 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 67.00 | 56.33 | 1111 | 7731 | 0.1497 | 0.5000 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 68.70 | 56.33 | 1113 | 7933 | 0.1461 | 0.4960 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 70.50 | 56.33 | 1112 | 7990 | 0.1455 | 0.4972 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 72.20 | 56.33 | 1112 | 8053 | 0.1442 | 0.4955 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 73.90 | 56.33 | 1120 | 8150 | 0.1439 | 0.4943 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 75.60 | 56.33 | 1109 | 7992 | 0.1438 | 0.4938 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 77.30 | 56.33 | 1124 | 8135 | 0.1440 | 0.4961 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 79.00 | 56.33 | 1106 | 8048 | 0.1424 | 0.4950 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 80.70 | 56.33 | 1109 | 7920 | 0.1448 | 0.4944 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 82.40 | 56.33 | 1112 | 7810 | 0.1460 | 0.4974 |