LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 94.30 | 56.33 | 1204 | 6924 | 0.1739 | 0.5445 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 95.70 | 27.76 | 1146 | 6712 | 0.1708 | 0.5657 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 2.30 | 56.33 | 313 | 255 | 1.2429 | 0.5908 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 4.00 | 56.33 | 352 | 303 | 1.1654 | 0.5471 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 5.70 | 56.33 | 388 | 342 | 1.1363 | 0.5099 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 7.40 | 56.33 | 426 | 385 | 1.1112 | 0.5019 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 9.10 | 56.33 | 464 | 424 | 1.0982 | 0.5345 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 10.80 | 56.33 | 494 | 465 | 1.0677 | 0.6105 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 12.50 | 56.33 | 524 | 510 | 1.0326 | 0.6759 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 14.20 | 56.33 | 642 | 634 | 1.0223 | 0.8295 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 15.90 | 56.33 | 739 | 726 | 1.0338 | 0.8637 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 17.60 | 56.33 | 824 | 868 | 0.9580 | 0.8396 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 19.30 | 56.33 | 881 | 1090 | 0.8440 | 0.8151 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 21.00 | 56.33 | 869 | 1286 | 0.7041 | 0.7593 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 22.80 | 56.33 | 878 | 1460 | 0.6186 | 0.7304 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 24.50 | 56.33 | 866 | 1615 | 0.5498 | 0.6985 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 26.20 | 56.33 | 900 | 1764 | 0.5220 | 0.6903 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 27.90 | 56.33 | 894 | 1907 | 0.4803 | 0.6700 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 29.60 | 56.33 | 914 | 2050 | 0.4569 | 0.6584 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 31.30 | 56.33 | 908 | 2241 | 0.4141 | 0.6410 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 33.00 | 56.33 | 942 | 2479 | 0.3895 | 0.6320 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 34.70 | 56.33 | 977 | 2720 | 0.3699 | 0.6205 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 36.40 | 56.33 | 958 | 2958 | 0.3320 | 0.6023 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 38.10 | 56.33 | 989 | 3168 | 0.3193 | 0.5958 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 39.80 | 56.33 | 973 | 3393 | 0.2926 | 0.5802 |