LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 29.70 | 770.96 | 1575 | 3022 | 0.5222 | 0.4368 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 31.90 | 770.96 | 1579 | 3294 | 0.4804 | 0.4079 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 34.10 | 770.96 | 1586 | 3605 | 0.4409 | 0.3825 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 36.40 | 770.96 | 1585 | 3985 | 0.3987 | 0.3550 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 38.60 | 770.96 | 1584 | 4421 | 0.3592 | 0.3304 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 40.80 | 770.96 | 1600 | 4874 | 0.3290 | 0.3155 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 43.00 | 770.96 | 1617 | 5280 | 0.3069 | 0.3055 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 45.30 | 770.96 | 1616 | 5677 | 0.2852 | 0.2922 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 47.50 | 770.96 | 1617 | 6082 | 0.2664 | 0.2814 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 49.70 | 770.96 | 1629 | 6511 | 0.2506 | 0.2745 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 51.90 | 770.96 | 1637 | 6944 | 0.2360 | 0.2675 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 54.10 | 770.96 | 1662 | 7405 | 0.2248 | 0.2647 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 56.40 | 770.96 | 1666 | 7845 | 0.2127 | 0.2582 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 58.60 | 770.96 | 1674 | 8264 | 0.2029 | 0.2536 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 60.80 | 770.96 | 1651 | 8711 | 0.1898 | 0.2424 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 63.00 | 770.96 | 1671 | 9152 | 0.1828 | 0.2413 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 65.30 | 770.96 | 1671 | 9591 | 0.1744 | 0.2362 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 67.50 | 770.96 | 1682 | 9939 | 0.1695 | 0.2349 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 69.70 | 770.96 | 1692 | 10312 | 0.1642 | 0.2330 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 71.90 | 770.96 | 1705 | 10631 | 0.1605 | 0.2325 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 74.10 | 770.96 | 1708 | 10921 | 0.1565 | 0.2303 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 76.40 | 770.96 | 1719 | 11184 | 0.1538 | 0.2302 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 78.60 | 770.96 | 1709 | 11443 | 0.1495 | 0.2261 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 80.80 | 770.96 | 1713 | 11725 | 0.1462 | 0.2246 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 83.10 | 770.96 | 1728 | 12002 | 0.1441 | 0.2251 |