LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 80.80 | 770.96 | 10132 | 11725 | 0.8642 | 0.9257 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 83.10 | 770.96 | 10395 | 12002 | 0.8661 | 0.9271 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 85.30 | 770.96 | 10749 | 12277 | 0.8756 | 0.9331 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 87.50 | 770.96 | 11054 | 12567 | 0.8795 | 0.9354 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 2.90 | 770.96 | 925 | 886 | 1.0440 | 1.5079 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 5.10 | 770.96 | 1039 | 984 | 1.0557 | 1.3602 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 7.30 | 770.96 | 1125 | 1067 | 1.0547 | 1.2499 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 9.60 | 770.96 | 1227 | 1178 | 1.0416 | 1.1417 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 11.90 | 770.96 | 1396 | 1319 | 1.0581 | 1.1521 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 14.10 | 770.96 | 1566 | 1478 | 1.0594 | 1.1259 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 16.40 | 770.96 | 1724 | 1625 | 1.0612 | 1.1134 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 18.60 | 770.96 | 1832 | 1786 | 1.0254 | 1.0420 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 20.80 | 770.96 | 1950 | 1959 | 0.9953 | 0.9928 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 23.00 | 770.96 | 2084 | 2193 | 0.9504 | 0.9329 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 25.30 | 770.96 | 2238 | 2456 | 0.9108 | 0.8904 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 27.50 | 770.96 | 2416 | 2754 | 0.8770 | 0.8609 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 29.70 | 770.96 | 2631 | 3022 | 0.8705 | 0.8634 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 31.90 | 770.96 | 2797 | 3294 | 0.8488 | 0.8488 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 34.10 | 770.96 | 2989 | 3605 | 0.8291 | 0.8378 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 36.40 | 770.96 | 3200 | 3985 | 0.8028 | 0.8220 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 38.60 | 770.96 | 3440 | 4421 | 0.7778 | 0.8089 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 40.80 | 770.96 | 3727 | 4874 | 0.7643 | 0.8065 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 43.00 | 770.96 | 3966 | 5280 | 0.7510 | 0.8028 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 45.30 | 770.96 | 4242 | 5677 | 0.7470 | 0.8064 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 47.50 | 770.96 | 4532 | 6082 | 0.7450 | 0.8109 |