LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 85.30 | 770.96 | 1733 | 12277 | 0.1412 | 0.2239 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 87.50 | 770.96 | 1754 | 12567 | 0.1396 | 0.2254 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 2.90 | 770.96 | 906 | 886 | 1.0224 | 1.2646 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 5.10 | 770.96 | 1008 | 984 | 1.0228 | 1.1326 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 7.30 | 770.96 | 1089 | 1067 | 1.0193 | 1.0839 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 9.60 | 770.96 | 1193 | 1178 | 1.0114 | 1.0307 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 11.90 | 770.96 | 1294 | 1319 | 0.9800 | 0.9458 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 14.10 | 770.96 | 1404 | 1478 | 0.9495 | 0.8913 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 16.40 | 770.96 | 1447 | 1625 | 0.8905 | 0.7954 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 18.60 | 770.96 | 1492 | 1786 | 0.8347 | 0.7220 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 20.80 | 770.96 | 1466 | 1959 | 0.7483 | 0.6122 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 23.00 | 770.96 | 1460 | 2193 | 0.6658 | 0.5268 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 25.30 | 770.96 | 1481 | 2456 | 0.6029 | 0.4770 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 27.50 | 770.96 | 1476 | 2754 | 0.5357 | 0.4228 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 29.70 | 770.96 | 1478 | 3022 | 0.4887 | 0.3899 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 31.90 | 770.96 | 1490 | 3294 | 0.4518 | 0.3675 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 34.10 | 770.96 | 1478 | 3605 | 0.4096 | 0.3382 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 36.40 | 770.96 | 1481 | 3985 | 0.3714 | 0.3161 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 38.60 | 770.96 | 1502 | 4421 | 0.3397 | 0.3025 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 40.80 | 770.96 | 1480 | 4874 | 0.3038 | 0.2776 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 43.00 | 770.96 | 1523 | 5280 | 0.2884 | 0.2772 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 45.30 | 770.96 | 1524 | 5677 | 0.2684 | 0.2662 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 47.50 | 770.96 | 1541 | 6082 | 0.2532 | 0.2605 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 49.70 | 770.96 | 1560 | 6511 | 0.2395 | 0.2564 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 51.90 | 770.96 | 1559 | 6944 | 0.2244 | 0.2476 |