LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 49.70 | 770.96 | 4803 | 6511 | 0.7374 | 0.8103 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 51.90 | 770.96 | 5060 | 6944 | 0.7283 | 0.8084 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 54.10 | 770.96 | 5420 | 7405 | 0.7316 | 0.8160 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 56.40 | 770.96 | 5680 | 7845 | 0.7237 | 0.8142 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 58.60 | 770.96 | 5988 | 8264 | 0.7241 | 0.8182 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 60.80 | 770.96 | 6246 | 8711 | 0.7167 | 0.8167 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 63.00 | 770.96 | 6523 | 9152 | 0.7125 | 0.8170 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 65.30 | 770.96 | 6808 | 9591 | 0.7094 | 0.8177 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 67.50 | 770.96 | 7019 | 9939 | 0.7058 | 0.8175 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 69.70 | 770.96 | 7244 | 10312 | 0.7021 | 0.8171 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 71.90 | 770.96 | 7437 | 10631 | 0.6991 | 0.8164 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 74.10 | 770.96 | 7624 | 10921 | 0.6978 | 0.8170 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 76.40 | 770.96 | 7801 | 11184 | 0.6971 | 0.8175 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 78.60 | 770.96 | 7940 | 11443 | 0.6935 | 0.8153 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 80.80 | 770.96 | 8125 | 11725 | 0.6928 | 0.8165 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 83.10 | 770.96 | 8326 | 12002 | 0.6936 | 0.8182 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 85.30 | 770.96 | 8452 | 12277 | 0.6884 | 0.8152 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 87.50 | 770.96 | 8436 | 12567 | 0.6715 | 0.8022 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 2.90 | 770.96 | 895 | 886 | 1.0096 | 1.2129 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 5.10 | 770.96 | 1005 | 984 | 1.0208 | 1.1511 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 7.30 | 770.96 | 1082 | 1067 | 1.0138 | 1.0699 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 9.60 | 770.96 | 1190 | 1178 | 1.0096 | 1.0341 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 11.90 | 770.96 | 1324 | 1319 | 1.0033 | 1.0075 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 14.10 | 770.96 | 1489 | 1478 | 1.0068 | 1.0134 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 16.40 | 770.96 | 1630 | 1625 | 1.0030 | 1.0043 |