LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 2 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 2. - Dataset (ID:20310)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 10.16 | 21.74 | 12 | 463 | 0.0259 | -0.1259 | MN20160310_N01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 10.16 | 21.74 | 993 | 463 | 2.1417 | 1.3766 | MN20160310_N01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 10.16 | 21.74 | 2 | 463 | 0.0043 | -0.4175 | MN20160310_N01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 10.16 | 21.74 | 1031 | 463 | 2.2237 | 1.3969 | MN20160310_N01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 12.13 | 21.74 | 12 | 496 | 0.0242 | -0.1234 | MN20160310_N01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 12.13 | 21.74 | 902 | 496 | 1.8172 | 1.2830 | MN20160310_N01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 12.13 | 21.74 | 52 | 496 | 0.1048 | 0.2132 | MN20160310_N01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 12.13 | 21.74 | 1013 | 496 | 2.0409 | 1.3425 | MN20160310_N01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 12.13 | 21.74 | 3 | 496 | 0.0060 | -0.3552 | MN20160310_N01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 12.13 | 21.74 | 1081 | 496 | 2.1779 | 1.3765 | MN20160310_N01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 14.10 | 21.74 | 13 | 540 | 0.0240 | -0.1050 | MN20160310_N01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 14.10 | 21.74 | 974 | 540 | 1.8006 | 1.2705 | MN20160310_N01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 14.10 | 21.74 | 175 | 540 | 0.3235 | 0.5680 | MN20160310_N01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 14.10 | 21.74 | 1056 | 540 | 1.9522 | 1.3104 | MN20160310_N01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 14.10 | 21.74 | 2 | 540 | 0.0037 | -0.4022 | MN20160310_N01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 14.10 | 21.74 | 1160 | 540 | 2.1445 | 1.3577 | MN20160310_N01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 16.07 | 21.74 | 1 | 597 | 0.0017 | -0.4748 | MN20160310_N01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 16.07 | 21.74 | 1055 | 597 | 1.7646 | 1.2522 | MN20160310_N01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 16.07 | 21.74 | 238 | 597 | 0.3981 | 0.6496 | MN20160310_N01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 16.07 | 21.74 | 1167 | 597 | 1.9520 | 1.3003 | MN20160310_N01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 16.07 | 21.74 | 4 | 597 | 0.0067 | -0.2982 | MN20160310_N01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 16.07 | 21.74 | 1277 | 597 | 2.1360 | 1.3440 | MN20160310_N01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 18.04 | 21.74 | 26 | 750 | 0.0346 | 0.0356 | MN20160310_N01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 18.04 | 21.74 | 1156 | 750 | 1.5402 | 1.1764 | MN20160310_N01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 18.04 | 21.74 | 751 | 750 | 1.0006 | 1.0002 | MN20160310_N01 | H05 |