LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 2 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 2. - Dataset (ID:20310)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 2.24 | 21.74 | 464 | 183 | 2.5276 | 1.7031 | MN20160310_N01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 2.24 | 21.74 | 1 | 183 | 0.0054 | -0.6323 | MN20160310_N01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 2.24 | 21.74 | 602 | 183 | 3.2794 | 1.9418 | MN20160310_N01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 2.24 | 21.74 | 1 | 183 | 0.0054 | -0.6323 | MN20160310_N01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 2.24 | 21.74 | 605 | 183 | 3.2957 | 1.9465 | MN20160310_N01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 4.24 | 21.74 | 1 | 317 | 0.0031 | -0.5487 | MN20160310_N01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 4.24 | 21.74 | 686 | 317 | 2.1587 | 1.4400 | MN20160310_N01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 4.24 | 21.74 | 1 | 317 | 0.0031 | -0.5487 | MN20160310_N01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 4.24 | 21.74 | 753 | 317 | 2.3695 | 1.4995 | MN20160310_N01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 4.24 | 21.74 | 2 | 317 | 0.0063 | -0.4602 | MN20160310_N01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 4.24 | 21.74 | 826 | 317 | 2.5992 | 1.5600 | MN20160310_N01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 6.21 | 21.74 | 1 | 392 | 0.0026 | -0.5219 | MN20160310_N01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 6.21 | 21.74 | 773 | 392 | 1.9719 | 1.3535 | MN20160310_N01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 6.21 | 21.74 | 1 | 392 | 0.0026 | -0.5219 | MN20160310_N01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 6.21 | 21.74 | 846 | 392 | 2.1582 | 1.4049 | MN20160310_N01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 6.21 | 21.74 | 1 | 392 | 0.0026 | -0.5219 | MN20160310_N01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 6.21 | 21.74 | 912 | 392 | 2.3265 | 1.4486 | MN20160310_N01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 8.19 | 21.74 | 10 | 439 | 0.0227 | -0.1639 | MN20160310_N01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 8.19 | 21.74 | 856 | 439 | 1.9461 | 1.3317 | MN20160310_N01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 8.19 | 21.74 | 2 | 439 | 0.0045 | -0.4230 | MN20160310_N01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 8.19 | 21.74 | 944 | 439 | 2.1462 | 1.3849 | MN20160310_N01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 8.19 | 21.74 | 3 | 439 | 0.0068 | -0.3665 | MN20160310_N01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 8.19 | 21.74 | 975 | 439 | 2.2166 | 1.4027 | MN20160310_N01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 10.16 | 21.74 | 13 | 463 | 0.0280 | -0.1100 | MN20160310_N01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 10.16 | 21.74 | 875 | 463 | 1.8872 | 1.3095 | MN20160310_N01 | E20 |