LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 1 | 14.50 | 770.25 | 1269 | 1497 | 0.8476 | 0.6831 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 16.73 | 770.25 | 1241 | 1664 | 0.7456 | 0.5358 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 16.73 | 770.25 | 1311 | 1664 | 0.7876 | 0.6135 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 18.95 | 770.25 | 1226 | 1832 | 0.6690 | 0.4502 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 18.95 | 770.25 | 1351 | 1832 | 0.7372 | 0.5673 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 21.17 | 770.25 | 1224 | 2008 | 0.6095 | 0.3979 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 21.17 | 770.25 | 1349 | 2008 | 0.6717 | 0.4998 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 23.39 | 770.25 | 1221 | 2244 | 0.5440 | 0.3480 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 23.39 | 770.25 | 1350 | 2244 | 0.6015 | 0.4386 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 25.62 | 770.25 | 1225 | 2514 | 0.4871 | 0.3123 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 25.62 | 770.25 | 1342 | 2514 | 0.5336 | 0.3844 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 27.84 | 770.25 | 1221 | 2833 | 0.4309 | 0.2778 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 27.84 | 770.25 | 1355 | 2833 | 0.4781 | 0.3506 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 30.06 | 770.25 | 1217 | 3106 | 0.3918 | 0.2553 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 30.06 | 770.25 | 1338 | 3106 | 0.4308 | 0.3159 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 32.28 | 770.25 | 1222 | 3392 | 0.3602 | 0.2408 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 32.28 | 770.25 | 1359 | 3392 | 0.4006 | 0.3040 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 34.50 | 770.25 | 1212 | 3712 | 0.3265 | 0.2212 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 34.50 | 770.25 | 1354 | 3712 | 0.3648 | 0.2823 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 36.73 | 770.25 | 1220 | 4086 | 0.2986 | 0.2105 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 36.73 | 770.25 | 1351 | 4086 | 0.3306 | 0.2629 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 38.95 | 770.25 | 1208 | 4543 | 0.2659 | 0.1921 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 38.95 | 770.25 | 1348 | 4543 | 0.2967 | 0.2443 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 41.17 | 770.25 | 1226 | 5010 | 0.2447 | 0.1877 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 41.17 | 770.25 | 1357 | 5010 | 0.2708 | 0.2332 | MN20160304_L02 | I10 |