LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 21.17 | 770.25 | 1580 | 2008 | 0.7867 | 0.6814 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 23.39 | 770.25 | 1436 | 2244 | 0.6398 | 0.4974 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 23.39 | 770.25 | 1581 | 2244 | 0.7044 | 0.5937 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 25.62 | 770.25 | 1420 | 2514 | 0.5646 | 0.4309 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 25.62 | 770.25 | 1557 | 2514 | 0.6191 | 0.5103 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 27.84 | 770.25 | 1402 | 2833 | 0.4947 | 0.3753 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 27.84 | 770.25 | 1600 | 2833 | 0.5646 | 0.4755 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 30.06 | 770.25 | 1403 | 3106 | 0.4517 | 0.3473 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 30.06 | 770.25 | 1577 | 3106 | 0.5077 | 0.4279 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 32.28 | 770.25 | 1418 | 3392 | 0.4179 | 0.3302 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 32.28 | 770.25 | 1568 | 3392 | 0.4621 | 0.3942 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 34.50 | 770.25 | 1428 | 3712 | 0.3847 | 0.3127 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 34.50 | 770.25 | 1586 | 3712 | 0.4273 | 0.3749 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 36.73 | 770.25 | 1397 | 4086 | 0.3419 | 0.2806 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 36.73 | 770.25 | 1613 | 4086 | 0.3948 | 0.3594 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 38.95 | 770.25 | 1381 | 4543 | 0.3039 | 0.2561 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 38.95 | 770.25 | 1611 | 4543 | 0.3545 | 0.3340 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 41.17 | 770.25 | 1417 | 5010 | 0.2828 | 0.2531 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 41.17 | 770.25 | 1647 | 5010 | 0.3287 | 0.3249 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 43.39 | 770.25 | 1445 | 5404 | 0.2674 | 0.2509 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 43.39 | 770.25 | 1631 | 5404 | 0.3018 | 0.3059 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 45.61 | 770.25 | 1425 | 5813 | 0.2451 | 0.2349 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 45.61 | 770.25 | 1674 | 5813 | 0.2880 | 0.3050 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 47.83 | 770.25 | 1407 | 6223 | 0.2261 | 0.2213 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 47.83 | 770.25 | 1679 | 6223 | 0.2698 | 0.2950 | MN20160304_L02 | J22 |