LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 5.44 | 770.25 | 1062 | 1012 | 1.0486 | 1.2556 | MN20160304_L02 | E22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 5.44 | 770.25 | 1027 | 1012 | 1.0141 | 1.0720 | MN20160304_L02 | N21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 7.66 | 770.25 | 1160 | 1090 | 1.0642 | 1.2646 | MN20160304_L02 | E22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 7.66 | 770.25 | 1094 | 1090 | 1.0037 | 1.0147 | MN20160304_L02 | N21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 10.06 | 770.25 | 1274 | 1218 | 1.0455 | 1.1393 | MN20160304_L02 | E22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 10.06 | 770.25 | 1225 | 1218 | 1.0053 | 1.0161 | MN20160304_L02 | N21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 12.28 | 770.25 | 1488 | 1358 | 1.0956 | 1.2362 | MN20160304_L02 | E22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 12.28 | 770.25 | 1366 | 1358 | 1.0058 | 1.0142 | MN20160304_L02 | N21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 14.50 | 770.25 | 1716 | 1497 | 1.1461 | 1.3056 | MN20160304_L02 | E22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 14.50 | 770.25 | 1593 | 1497 | 1.0640 | 1.1336 | MN20160304_L02 | N21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 16.73 | 770.25 | 1834 | 1664 | 1.1018 | 1.1823 | MN20160304_L02 | E22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 16.73 | 770.25 | 1755 | 1664 | 1.0544 | 1.0976 | MN20160304_L02 | N21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 18.95 | 770.25 | 1951 | 1832 | 1.0647 | 1.1028 | MN20160304_L02 | E22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 18.95 | 770.25 | 1863 | 1832 | 1.0166 | 1.0266 | MN20160304_L02 | N21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 21.17 | 770.25 | 2075 | 2008 | 1.0332 | 1.0478 | MN20160304_L02 | E22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 21.17 | 770.25 | 2022 | 2008 | 1.0068 | 1.0098 | MN20160304_L02 | N21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 23.39 | 770.25 | 2235 | 2244 | 0.9958 | 0.9945 | MN20160304_L02 | E22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 23.39 | 770.25 | 2204 | 2244 | 0.9820 | 0.9765 | MN20160304_L02 | N21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 25.62 | 770.25 | 2517 | 2514 | 1.0008 | 1.0010 | MN20160304_L02 | E22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 25.62 | 770.25 | 2431 | 2514 | 0.9667 | 0.9607 | MN20160304_L02 | N21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 27.84 | 770.25 | 2804 | 2833 | 0.9895 | 0.9888 | MN20160304_L02 | E22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 27.84 | 770.25 | 2643 | 2833 | 0.9327 | 0.9272 | MN20160304_L02 | N21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 30.06 | 770.25 | 2987 | 3106 | 0.9617 | 0.9615 | MN20160304_L02 | E22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 30.06 | 770.25 | 2879 | 3106 | 0.9269 | 0.9259 | MN20160304_L02 | N21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 32.28 | 770.25 | 3172 | 3392 | 0.9349 | 0.9380 | MN20160304_L02 | E22 |