LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 78.98 | 770.25 | 11943 | 11518 | 1.0369 | 1.0186 | MN20160304_L02 | H15 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 81.20 | 770.25 | 9523 | 11766 | 0.8093 | 0.8953 | MN20160304_L02 | D03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 81.20 | 770.25 | 10102 | 11766 | 0.8586 | 0.9239 | MN20160304_L02 | D05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 81.20 | 770.25 | 12544 | 11766 | 1.0661 | 1.0328 | MN20160304_L02 | G14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 81.20 | 770.25 | 12282 | 11766 | 1.0438 | 1.0219 | MN20160304_L02 | H15 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 83.42 | 770.25 | 9649 | 12031 | 0.8020 | 0.8917 | MN20160304_L02 | D03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 83.42 | 770.25 | 10285 | 12031 | 0.8548 | 0.9224 | MN20160304_L02 | D05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 83.42 | 770.25 | 12827 | 12031 | 1.0661 | 1.0325 | MN20160304_L02 | G14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 83.42 | 770.25 | 12760 | 12031 | 1.0605 | 1.0299 | MN20160304_L02 | H15 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 85.64 | 770.25 | 9679 | 12287 | 0.7877 | 0.8841 | MN20160304_L02 | D03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 85.64 | 770.25 | 10363 | 12287 | 0.8434 | 0.9165 | MN20160304_L02 | D05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 85.64 | 770.25 | 13226 | 12287 | 1.0764 | 1.0372 | MN20160304_L02 | G14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 85.64 | 770.25 | 13125 | 12287 | 1.0682 | 1.0333 | MN20160304_L02 | H15 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 87.86 | 770.25 | 9758 | 12543 | 0.7779 | 0.8791 | MN20160304_L02 | D03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 87.86 | 770.25 | 10512 | 12543 | 0.8381 | 0.9141 | MN20160304_L02 | D05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 87.86 | 770.25 | 13595 | 12543 | 1.0838 | 1.0404 | MN20160304_L02 | G14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 87.86 | 770.25 | 13600 | 12543 | 1.0842 | 1.0406 | MN20160304_L02 | H15 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 3.21 | 770.25 | 780 | 904 | 0.8622 | 0.0557 | MN20160304_L02 | E16 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 3.21 | 770.25 | 991 | 904 | 1.0955 | 1.9631 | MN20160304_L02 | E21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 5.44 | 770.25 | 898 | 1012 | 0.8867 | 0.4749 | MN20160304_L02 | E16 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 5.44 | 770.25 | 1054 | 1012 | 1.0407 | 1.2128 | MN20160304_L02 | E21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 7.66 | 770.25 | 966 | 1090 | 0.8862 | 0.5715 | MN20160304_L02 | E16 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 7.66 | 770.25 | 1139 | 1090 | 1.0450 | 1.1835 | MN20160304_L02 | E21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 10.06 | 770.25 | 1079 | 1218 | 0.8855 | 0.6643 | MN20160304_L02 | E16 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 10.06 | 770.25 | 1259 | 1218 | 1.0332 | 1.1013 | MN20160304_L02 | E21 |