LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Neratinib | 1 | 38.95 | 770.25 | 1079 | 4543 | 0.2375 | 0.1407 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 38.95 | 770.25 | 1486 | 4543 | 0.3270 | 0.2926 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 41.17 | 770.25 | 1085 | 5010 | 0.2165 | 0.1352 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 41.17 | 770.25 | 1398 | 5010 | 0.2790 | 0.2469 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 43.39 | 770.25 | 1110 | 5404 | 0.2054 | 0.1388 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 43.39 | 770.25 | 1438 | 5404 | 0.2661 | 0.2487 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 45.61 | 770.25 | 1116 | 5813 | 0.1920 | 0.1356 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 45.61 | 770.25 | 1516 | 5813 | 0.2608 | 0.2614 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 47.83 | 770.25 | 1123 | 6223 | 0.1805 | 0.1332 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 47.83 | 770.25 | 1481 | 6223 | 0.2380 | 0.2422 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 50.05 | 770.25 | 1102 | 6629 | 0.1662 | 0.1223 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 50.05 | 770.25 | 1460 | 6629 | 0.2202 | 0.2287 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 52.27 | 770.25 | 1116 | 7058 | 0.1581 | 0.1230 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 52.27 | 770.25 | 1514 | 7058 | 0.2145 | 0.2355 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 54.49 | 770.25 | 1091 | 7555 | 0.1444 | 0.1115 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 54.49 | 770.25 | 1544 | 7555 | 0.2044 | 0.2351 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 56.71 | 770.25 | 1153 | 8001 | 0.1441 | 0.1269 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 56.71 | 770.25 | 1602 | 8001 | 0.2002 | 0.2422 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 58.94 | 770.25 | 1128 | 8444 | 0.1336 | 0.1168 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 58.94 | 770.25 | 1590 | 8444 | 0.1883 | 0.2334 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 61.16 | 770.25 | 1127 | 8892 | 0.1267 | 0.1139 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 61.16 | 770.25 | 1569 | 8892 | 0.1765 | 0.2234 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 63.39 | 770.25 | 1106 | 9326 | 0.1186 | 0.1058 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 63.39 | 770.25 | 1554 | 9326 | 0.1666 | 0.2154 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 65.61 | 770.25 | 1176 | 9736 | 0.1208 | 0.1226 | MN20160304_L02 | E14 |