LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 1 | 80.48 | 771.67 | 1747 | 11685 | 0.1495 | 0.2317 | MN20160304_L01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 82.69 | 771.67 | 1431 | 11974 | 0.1195 | 0.1690 | MN20160304_L01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 82.69 | 771.67 | 1745 | 11974 | 0.1457 | 0.2291 | MN20160304_L01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 84.92 | 771.67 | 1444 | 12266 | 0.1177 | 0.1700 | MN20160304_L01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 84.92 | 771.67 | 1762 | 12266 | 0.1436 | 0.2299 | MN20160304_L01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 87.14 | 771.67 | 1425 | 12592 | 0.1132 | 0.1645 | MN20160304_L01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 87.14 | 771.67 | 1760 | 12592 | 0.1398 | 0.2271 | MN20160304_L01 | K06 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 2.49 | 771.67 | 873 | 867 | 1.0061 | 1.0725 | MN20160304_L01 | C12 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 2.49 | 771.67 | 802 | 867 | 0.9242 | 0.2557 | MN20160304_L01 | H03 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 4.71 | 771.67 | 1005 | 956 | 1.0508 | 1.3475 | MN20160304_L01 | C12 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 4.71 | 771.67 | 925 | 956 | 0.9672 | 0.7957 | MN20160304_L01 | H03 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 6.94 | 771.67 | 1080 | 1045 | 1.0334 | 1.1558 | MN20160304_L01 | C12 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 6.94 | 771.67 | 992 | 1045 | 0.9492 | 0.7752 | MN20160304_L01 | H03 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 9.16 | 771.67 | 1161 | 1138 | 1.0198 | 1.0710 | MN20160304_L01 | C12 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 9.16 | 771.67 | 1093 | 1138 | 0.9600 | 0.8598 | MN20160304_L01 | H03 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 11.56 | 771.67 | 1305 | 1280 | 1.0190 | 1.0523 | MN20160304_L01 | C12 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 11.56 | 771.67 | 1185 | 1280 | 0.9253 | 0.7985 | MN20160304_L01 | H03 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 13.78 | 771.67 | 1484 | 1459 | 1.0166 | 1.0362 | MN20160304_L01 | C12 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 13.78 | 771.67 | 1345 | 1459 | 0.9214 | 0.8297 | MN20160304_L01 | H03 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 16.00 | 771.67 | 1604 | 1585 | 1.0117 | 1.0225 | MN20160304_L01 | C12 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 16.00 | 771.67 | 1471 | 1585 | 0.9278 | 0.8608 | MN20160304_L01 | H03 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 18.22 | 771.67 | 1740 | 1741 | 0.9992 | 0.9987 | MN20160304_L01 | C12 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 18.22 | 771.67 | 1602 | 1741 | 0.9200 | 0.8628 | MN20160304_L01 | H03 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 20.44 | 771.67 | 1967 | 1910 | 1.0294 | 1.0448 | MN20160304_L01 | C12 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 20.44 | 771.67 | 1731 | 1910 | 0.9059 | 0.8544 | MN20160304_L01 | H03 |