LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 87.14 | 771.67 | 2013 | 12592 | 0.1599 | 0.2687 | MN20160304_L01 | L05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 2.49 | 771.67 | 811 | 867 | 0.9346 | 0.3413 | MN20160304_L01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 2.49 | 771.67 | 895 | 867 | 1.0314 | 1.4008 | MN20160304_L01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 4.71 | 771.67 | 903 | 956 | 0.9442 | 0.6614 | MN20160304_L01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 4.71 | 771.67 | 988 | 956 | 1.0331 | 1.2216 | MN20160304_L01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 6.94 | 771.67 | 974 | 1045 | 0.9320 | 0.7025 | MN20160304_L01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 6.94 | 771.67 | 1059 | 1045 | 1.0133 | 1.0612 | MN20160304_L01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 9.16 | 771.67 | 1058 | 1138 | 0.9293 | 0.7550 | MN20160304_L01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 9.16 | 771.67 | 1155 | 1138 | 1.0145 | 1.0520 | MN20160304_L01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 11.56 | 771.67 | 1164 | 1280 | 0.9089 | 0.7550 | MN20160304_L01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 11.56 | 771.67 | 1278 | 1280 | 0.9980 | 0.9944 | MN20160304_L01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 13.78 | 771.67 | 1266 | 1459 | 0.8673 | 0.7131 | MN20160304_L01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 13.78 | 771.67 | 1398 | 1459 | 0.9577 | 0.9082 | MN20160304_L01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 16.00 | 771.67 | 1334 | 1585 | 0.8414 | 0.6937 | MN20160304_L01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 16.00 | 771.67 | 1496 | 1585 | 0.9436 | 0.8912 | MN20160304_L01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 18.22 | 771.67 | 1362 | 1741 | 0.7821 | 0.6224 | MN20160304_L01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 18.22 | 771.67 | 1506 | 1741 | 0.8648 | 0.7673 | MN20160304_L01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 20.44 | 771.67 | 1373 | 1910 | 0.7185 | 0.5534 | MN20160304_L01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 20.44 | 771.67 | 1521 | 1910 | 0.7960 | 0.6799 | MN20160304_L01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 22.66 | 771.67 | 1358 | 2141 | 0.6341 | 0.4679 | MN20160304_L01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 22.66 | 771.67 | 1508 | 2141 | 0.7042 | 0.5761 | MN20160304_L01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 24.89 | 771.67 | 1369 | 2397 | 0.5710 | 0.4198 | MN20160304_L01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 24.89 | 771.67 | 1508 | 2397 | 0.6289 | 0.5062 | MN20160304_L01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 27.11 | 771.67 | 1307 | 2675 | 0.4886 | 0.3415 | MN20160304_L01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 27.11 | 771.67 | 1506 | 2675 | 0.5630 | 0.4518 | MN20160304_L01 | H10 |