LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 73.76 | 771.67 | 5469 | 10851 | 0.5040 | 0.6711 | MN20160304_L01 | I11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 73.76 | 771.67 | 5953 | 10851 | 0.5486 | 0.7087 | MN20160304_L01 | N13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 76.02 | 771.67 | 5802 | 11106 | 0.5224 | 0.6894 | MN20160304_L01 | I11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 76.02 | 771.67 | 6244 | 11106 | 0.5622 | 0.7219 | MN20160304_L01 | N13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 78.25 | 771.67 | 6014 | 11367 | 0.5290 | 0.6974 | MN20160304_L01 | I11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 78.25 | 771.67 | 6532 | 11367 | 0.5746 | 0.7339 | MN20160304_L01 | N13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 80.48 | 771.67 | 6261 | 11685 | 0.5358 | 0.7057 | MN20160304_L01 | I11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 80.48 | 771.67 | 6810 | 11685 | 0.5828 | 0.7427 | MN20160304_L01 | N13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 82.69 | 771.67 | 6532 | 11974 | 0.5455 | 0.7159 | MN20160304_L01 | I11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 82.69 | 771.67 | 7114 | 11974 | 0.5941 | 0.7533 | MN20160304_L01 | N13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 84.92 | 771.67 | 6834 | 12266 | 0.5571 | 0.7273 | MN20160304_L01 | I11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 84.92 | 771.67 | 7398 | 12266 | 0.6031 | 0.7620 | MN20160304_L01 | N13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 87.14 | 771.67 | 7079 | 12592 | 0.5622 | 0.7336 | MN20160304_L01 | I11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 87.14 | 771.67 | 7717 | 12592 | 0.6128 | 0.7711 | MN20160304_L01 | N13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 2.49 | 771.67 | 902 | 867 | 1.0395 | 1.5138 | MN20160304_L01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 2.49 | 771.67 | 933 | 867 | 1.0752 | 2.0691 | MN20160304_L01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 4.71 | 771.67 | 1003 | 956 | 1.0488 | 1.3324 | MN20160304_L01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 4.71 | 771.67 | 958 | 956 | 1.0017 | 1.0110 | MN20160304_L01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 6.94 | 771.67 | 1044 | 1045 | 0.9989 | 0.9951 | MN20160304_L01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 6.94 | 771.67 | 1127 | 1045 | 1.0783 | 1.3762 | MN20160304_L01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 9.16 | 771.67 | 1102 | 1138 | 0.9679 | 0.8872 | MN20160304_L01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 9.16 | 771.67 | 1248 | 1138 | 1.0962 | 1.3556 | MN20160304_L01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 11.56 | 771.67 | 1216 | 1280 | 0.9495 | 0.8632 | MN20160304_L01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 11.56 | 771.67 | 1375 | 1280 | 1.0737 | 1.2044 | MN20160304_L01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 13.78 | 771.67 | 1377 | 1459 | 0.9433 | 0.8770 | MN20160304_L01 | H06 |