LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Etoposide | 10 | 80.48 | 771.67 | 796 | 11685 | 0.0681 | 0.0079 | MN20160304_L01 | J18 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 80.48 | 771.67 | 816 | 11685 | 0.0698 | 0.0144 | MN20160304_L01 | J20 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 82.69 | 771.67 | 797 | 11974 | 0.0666 | 0.0082 | MN20160304_L01 | J18 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 82.69 | 771.67 | 805 | 11974 | 0.0672 | 0.0107 | MN20160304_L01 | J20 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 84.92 | 771.67 | 784 | 12266 | 0.0639 | 0.0040 | MN20160304_L01 | J18 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 84.92 | 771.67 | 851 | 12266 | 0.0694 | 0.0248 | MN20160304_L01 | J20 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 87.14 | 771.67 | 785 | 12592 | 0.0623 | 0.0043 | MN20160304_L01 | J18 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 87.14 | 771.67 | 801 | 12592 | 0.0636 | 0.0093 | MN20160304_L01 | J20 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 2.49 | 771.67 | 890 | 867 | 1.0256 | 1.3226 | MN20160304_L01 | I14 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 2.49 | 771.67 | 915 | 867 | 1.0545 | 1.7355 | MN20160304_L01 | L07 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 4.71 | 771.67 | 979 | 956 | 1.0237 | 1.1569 | MN20160304_L01 | I14 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 4.71 | 771.67 | 1044 | 956 | 1.0916 | 1.6546 | MN20160304_L01 | L07 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 6.94 | 771.67 | 1070 | 1045 | 1.0238 | 1.1104 | MN20160304_L01 | I14 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 6.94 | 771.67 | 1091 | 1045 | 1.0439 | 1.2063 | MN20160304_L01 | L07 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 9.16 | 771.67 | 1186 | 1138 | 1.0417 | 1.1511 | MN20160304_L01 | I14 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 9.16 | 771.67 | 1229 | 1138 | 1.0795 | 1.2921 | MN20160304_L01 | L07 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 11.56 | 771.67 | 1312 | 1280 | 1.0245 | 1.0674 | MN20160304_L01 | I14 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 11.56 | 771.67 | 1377 | 1280 | 1.0753 | 1.2088 | MN20160304_L01 | L07 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 13.78 | 771.67 | 1489 | 1459 | 1.0200 | 1.0436 | MN20160304_L01 | I14 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 13.78 | 771.67 | 1563 | 1459 | 1.0707 | 1.1543 | MN20160304_L01 | L07 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 16.00 | 771.67 | 1635 | 1585 | 1.0312 | 1.0601 | MN20160304_L01 | I14 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 16.00 | 771.67 | 1738 | 1585 | 1.0962 | 1.1848 | MN20160304_L01 | L07 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 18.22 | 771.67 | 1811 | 1741 | 1.0400 | 1.0679 | MN20160304_L01 | I14 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 18.22 | 771.67 | 1874 | 1741 | 1.0762 | 1.1290 | MN20160304_L01 | L07 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 20.44 | 771.67 | 2017 | 1910 | 1.0555 | 1.0844 | MN20160304_L01 | I14 |