LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 76.75 | 770.25 | 1727 | 11262 | 0.1533 | 0.2320 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 78.98 | 770.25 | 1512 | 11518 | 0.1313 | 0.1887 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 78.98 | 770.25 | 1703 | 11518 | 0.1479 | 0.2255 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 81.20 | 770.25 | 1520 | 11766 | 0.1292 | 0.1887 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 81.20 | 770.25 | 1713 | 11766 | 0.1456 | 0.2253 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 83.42 | 770.25 | 1530 | 12031 | 0.1272 | 0.1890 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 83.42 | 770.25 | 1730 | 12031 | 0.1438 | 0.2264 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 85.64 | 770.25 | 1520 | 12287 | 0.1237 | 0.1855 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 85.64 | 770.25 | 1752 | 12287 | 0.1426 | 0.2284 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 87.86 | 770.25 | 1537 | 12543 | 0.1225 | 0.1872 | MN20160304_L02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 87.86 | 770.25 | 1780 | 12543 | 0.1419 | 0.2313 | MN20160304_L02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 3.21 | 770.25 | 902 | 904 | 0.9971 | 0.9751 | MN20160304_L02 | D08 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 3.21 | 770.25 | 1019 | 904 | 1.1264 | 2.3412 | MN20160304_L02 | M17 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 5.44 | 770.25 | 995 | 1012 | 0.9825 | 0.9124 | MN20160304_L02 | D08 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 5.44 | 770.25 | 1146 | 1012 | 1.1316 | 1.7351 | MN20160304_L02 | M17 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 7.66 | 770.25 | 1072 | 1090 | 0.9835 | 0.9346 | MN20160304_L02 | D08 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 7.66 | 770.25 | 1252 | 1090 | 1.1486 | 1.6373 | MN20160304_L02 | M17 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 10.06 | 770.25 | 1214 | 1218 | 0.9963 | 0.9889 | MN20160304_L02 | D08 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 10.06 | 770.25 | 1347 | 1218 | 1.1055 | 1.3272 | MN20160304_L02 | M17 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 12.28 | 770.25 | 1287 | 1358 | 0.9476 | 0.8728 | MN20160304_L02 | D08 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 12.28 | 770.25 | 1447 | 1358 | 1.0654 | 1.1611 | MN20160304_L02 | M17 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 14.50 | 770.25 | 1391 | 1497 | 0.9290 | 0.8522 | MN20160304_L02 | D08 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 14.50 | 770.25 | 1563 | 1497 | 1.0439 | 1.0917 | MN20160304_L02 | M17 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 16.73 | 770.25 | 1466 | 1664 | 0.8807 | 0.7841 | MN20160304_L02 | D08 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 16.73 | 770.25 | 1492 | 1664 | 0.8964 | 0.8126 | MN20160304_L02 | M17 |