LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 87.86 | 770.25 | 4299 | 12543 | 0.3427 | 0.5329 | MN20160304_L02 | G10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 87.86 | 770.25 | 3616 | 12543 | 0.2883 | 0.4684 | MN20160304_L02 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 3.21 | 770.25 | 924 | 904 | 1.0214 | 1.1913 | MN20160304_L02 | F03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 3.21 | 770.25 | 896 | 904 | 0.9905 | 0.9191 | MN20160304_L02 | I05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 5.44 | 770.25 | 1016 | 1012 | 1.0032 | 1.0163 | MN20160304_L02 | F03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 5.44 | 770.25 | 976 | 1012 | 0.9637 | 0.8213 | MN20160304_L02 | I05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 7.66 | 770.25 | 1121 | 1090 | 1.0284 | 1.1152 | MN20160304_L02 | F03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 7.66 | 770.25 | 1049 | 1090 | 0.9624 | 0.8526 | MN20160304_L02 | I05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 10.06 | 770.25 | 1217 | 1218 | 0.9988 | 0.9963 | MN20160304_L02 | F03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 10.06 | 770.25 | 1138 | 1218 | 0.9339 | 0.8037 | MN20160304_L02 | I05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 12.28 | 770.25 | 1353 | 1358 | 0.9962 | 0.9908 | MN20160304_L02 | F03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 12.28 | 770.25 | 1257 | 1358 | 0.9255 | 0.8195 | MN20160304_L02 | I05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 14.50 | 770.25 | 1461 | 1497 | 0.9758 | 0.9495 | MN20160304_L02 | F03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 14.50 | 770.25 | 1408 | 1497 | 0.9404 | 0.8758 | MN20160304_L02 | I05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 16.73 | 770.25 | 1524 | 1664 | 0.9156 | 0.8475 | MN20160304_L02 | F03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 16.73 | 770.25 | 1486 | 1664 | 0.8928 | 0.8060 | MN20160304_L02 | I05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 18.95 | 770.25 | 1558 | 1832 | 0.8502 | 0.7566 | MN20160304_L02 | F03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 18.95 | 770.25 | 1499 | 1832 | 0.8180 | 0.7032 | MN20160304_L02 | I05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 21.17 | 770.25 | 1570 | 2008 | 0.7817 | 0.6737 | MN20160304_L02 | F03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 21.17 | 770.25 | 1531 | 2008 | 0.7623 | 0.6435 | MN20160304_L02 | I05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 23.39 | 770.25 | 1574 | 2244 | 0.7013 | 0.5891 | MN20160304_L02 | F03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 23.39 | 770.25 | 1546 | 2244 | 0.6888 | 0.5707 | MN20160304_L02 | I05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 25.62 | 770.25 | 1559 | 2514 | 0.6199 | 0.5114 | MN20160304_L02 | F03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 25.62 | 770.25 | 1541 | 2514 | 0.6128 | 0.5012 | MN20160304_L02 | I05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 27.84 | 770.25 | 1593 | 2833 | 0.5621 | 0.4720 | MN20160304_L02 | F03 |