LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 3.21 | 770.25 | 778 | 904 | 0.8600 | 0.0441 | MN20160304_L02 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 5.44 | 770.25 | 895 | 1012 | 0.8837 | 0.4625 | MN20160304_L02 | G10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 5.44 | 770.25 | 849 | 1012 | 0.8383 | 0.2796 | MN20160304_L02 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 7.66 | 770.25 | 967 | 1090 | 0.8872 | 0.5748 | MN20160304_L02 | G10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 7.66 | 770.25 | 902 | 1090 | 0.8275 | 0.3706 | MN20160304_L02 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 10.06 | 770.25 | 1054 | 1218 | 0.8650 | 0.6064 | MN20160304_L02 | G10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 10.06 | 770.25 | 1005 | 1218 | 0.8248 | 0.4949 | MN20160304_L02 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 12.28 | 770.25 | 1148 | 1358 | 0.8453 | 0.6286 | MN20160304_L02 | G10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 12.28 | 770.25 | 1110 | 1358 | 0.8173 | 0.5630 | MN20160304_L02 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 14.50 | 770.25 | 1315 | 1497 | 0.8783 | 0.7468 | MN20160304_L02 | G10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 14.50 | 770.25 | 1193 | 1497 | 0.7968 | 0.5782 | MN20160304_L02 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 16.73 | 770.25 | 1380 | 1664 | 0.8291 | 0.6897 | MN20160304_L02 | G10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 16.73 | 770.25 | 1231 | 1664 | 0.7396 | 0.5246 | MN20160304_L02 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 18.95 | 770.25 | 1418 | 1832 | 0.7738 | 0.6292 | MN20160304_L02 | G10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 18.95 | 770.25 | 1270 | 1832 | 0.6930 | 0.4917 | MN20160304_L02 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 21.17 | 770.25 | 1420 | 2008 | 0.7070 | 0.5565 | MN20160304_L02 | G10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 21.17 | 770.25 | 1244 | 2008 | 0.6194 | 0.4144 | MN20160304_L02 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 23.39 | 770.25 | 1441 | 2244 | 0.6420 | 0.5007 | MN20160304_L02 | G10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 23.39 | 770.25 | 1266 | 2244 | 0.5641 | 0.3799 | MN20160304_L02 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 25.62 | 770.25 | 1430 | 2514 | 0.5686 | 0.4368 | MN20160304_L02 | G10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 25.62 | 770.25 | 1255 | 2514 | 0.4990 | 0.3311 | MN20160304_L02 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 27.84 | 770.25 | 1456 | 2833 | 0.5138 | 0.4033 | MN20160304_L02 | G10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 27.84 | 770.25 | 1277 | 2833 | 0.4506 | 0.3087 | MN20160304_L02 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 30.06 | 770.25 | 1480 | 3106 | 0.4765 | 0.3835 | MN20160304_L02 | G10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 30.06 | 770.25 | 1254 | 3106 | 0.4037 | 0.2741 | MN20160304_L02 | N22 |