LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 85.64 | 770.25 | 10873 | 12287 | 0.8849 | 0.9397 | MN20160304_L02 | K14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 85.64 | 770.25 | 7913 | 12287 | 0.6440 | 0.7914 | MN20160304_L02 | L04 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 87.86 | 770.25 | 11271 | 12543 | 0.8986 | 0.9476 | MN20160304_L02 | K14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 87.86 | 770.25 | 7967 | 12543 | 0.6352 | 0.7867 | MN20160304_L02 | L04 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 3.21 | 770.25 | 766 | 904 | 0.8468 | -0.0236 | MN20160304_L02 | G13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 3.21 | 770.25 | 1051 | 904 | 1.1618 | 2.8176 | MN20160304_L02 | K07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 3.21 | 770.25 | 1012 | 904 | 1.1187 | 2.2434 | MN20160304_L02 | N12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 5.44 | 770.25 | 863 | 1012 | 0.8521 | 0.3337 | MN20160304_L02 | G13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 5.44 | 770.25 | 1149 | 1012 | 1.1345 | 1.7533 | MN20160304_L02 | K07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 5.44 | 770.25 | 1117 | 1012 | 1.1029 | 1.5632 | MN20160304_L02 | N12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 7.66 | 770.25 | 941 | 1090 | 0.8633 | 0.4914 | MN20160304_L02 | G13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 7.66 | 770.25 | 1247 | 1090 | 1.1440 | 1.6163 | MN20160304_L02 | K07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 7.66 | 770.25 | 1199 | 1090 | 1.1000 | 1.4191 | MN20160304_L02 | N12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 10.06 | 770.25 | 1035 | 1218 | 0.8494 | 0.5628 | MN20160304_L02 | G13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 10.06 | 770.25 | 1389 | 1218 | 1.1399 | 1.4377 | MN20160304_L02 | K07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 10.06 | 770.25 | 1327 | 1218 | 1.0890 | 1.2752 | MN20160304_L02 | N12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 12.28 | 770.25 | 1156 | 1358 | 0.8512 | 0.6425 | MN20160304_L02 | G13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 12.28 | 770.25 | 1540 | 1358 | 1.1339 | 1.3320 | MN20160304_L02 | K07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 12.28 | 770.25 | 1490 | 1358 | 1.0971 | 1.2398 | MN20160304_L02 | N12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 14.50 | 770.25 | 1274 | 1497 | 0.8509 | 0.6901 | MN20160304_L02 | G13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 14.50 | 770.25 | 1721 | 1497 | 1.1494 | 1.3126 | MN20160304_L02 | K07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 14.50 | 770.25 | 1680 | 1497 | 1.1221 | 1.2552 | MN20160304_L02 | N12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 16.73 | 770.25 | 1381 | 1664 | 0.8297 | 0.6908 | MN20160304_L02 | G13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 16.73 | 770.25 | 1845 | 1664 | 1.1084 | 1.1941 | MN20160304_L02 | K07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 16.73 | 770.25 | 1823 | 1664 | 1.0952 | 1.1705 | MN20160304_L02 | N12 |