LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 87.86 | 770.25 | 10539 | 12543 | 0.8402 | 0.9153 | MN20160304_L02 | N21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 3.21 | 770.25 | 946 | 904 | 1.0457 | 1.4252 | MN20160304_L02 | K14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 3.21 | 770.25 | 951 | 904 | 1.0513 | 1.4809 | MN20160304_L02 | L04 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 5.44 | 770.25 | 1041 | 1012 | 1.0279 | 1.1443 | MN20160304_L02 | K14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 5.44 | 770.25 | 1085 | 1012 | 1.0713 | 1.3813 | MN20160304_L02 | L04 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 7.66 | 770.25 | 1144 | 1090 | 1.0495 | 1.2027 | MN20160304_L02 | K14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 7.66 | 770.25 | 1139 | 1090 | 1.0450 | 1.1835 | MN20160304_L02 | L04 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 10.06 | 770.25 | 1276 | 1218 | 1.0472 | 1.1443 | MN20160304_L02 | K14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 10.06 | 770.25 | 1262 | 1218 | 1.0357 | 1.1089 | MN20160304_L02 | L04 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 12.28 | 770.25 | 1461 | 1358 | 1.0757 | 1.1867 | MN20160304_L02 | K14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 12.28 | 770.25 | 1427 | 1358 | 1.0507 | 1.1246 | MN20160304_L02 | L04 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 14.50 | 770.25 | 1638 | 1497 | 1.0940 | 1.1964 | MN20160304_L02 | K14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 14.50 | 770.25 | 1599 | 1497 | 1.0680 | 1.1419 | MN20160304_L02 | L04 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 16.73 | 770.25 | 1762 | 1664 | 1.0586 | 1.1051 | MN20160304_L02 | K14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 16.73 | 770.25 | 1780 | 1664 | 1.0694 | 1.1244 | MN20160304_L02 | L04 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 18.95 | 770.25 | 1866 | 1832 | 1.0183 | 1.0292 | MN20160304_L02 | K14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 18.95 | 770.25 | 1871 | 1832 | 1.0210 | 1.0335 | MN20160304_L02 | L04 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 21.17 | 770.25 | 2014 | 2008 | 1.0028 | 1.0040 | MN20160304_L02 | K14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 21.17 | 770.25 | 1972 | 2008 | 0.9819 | 0.9737 | MN20160304_L02 | L04 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 23.39 | 770.25 | 2173 | 2244 | 0.9681 | 0.9585 | MN20160304_L02 | K14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 23.39 | 770.25 | 2121 | 2244 | 0.9450 | 0.9280 | MN20160304_L02 | L04 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 25.62 | 770.25 | 2339 | 2514 | 0.9301 | 0.9168 | MN20160304_L02 | K14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 25.62 | 770.25 | 2304 | 2514 | 0.9162 | 0.9000 | MN20160304_L02 | L04 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 27.84 | 770.25 | 2544 | 2833 | 0.8977 | 0.8884 | MN20160304_L02 | K14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 27.84 | 770.25 | 2484 | 2833 | 0.8765 | 0.8646 | MN20160304_L02 | L04 |