LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 23.39 | 770.25 | 1914 | 2244 | 0.8528 | 0.8038 | MN20160304_L02 | H15 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 25.62 | 770.25 | 2211 | 2514 | 0.8792 | 0.8547 | MN20160304_L02 | D03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 25.62 | 770.25 | 2297 | 2514 | 0.9134 | 0.8966 | MN20160304_L02 | D05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 25.62 | 770.25 | 2189 | 2514 | 0.8704 | 0.8438 | MN20160304_L02 | G14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 25.62 | 770.25 | 2186 | 2514 | 0.8692 | 0.8424 | MN20160304_L02 | H15 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 27.84 | 770.25 | 2503 | 2833 | 0.8832 | 0.8722 | MN20160304_L02 | D03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 27.84 | 770.25 | 2564 | 2833 | 0.9048 | 0.8963 | MN20160304_L02 | D05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 27.84 | 770.25 | 2511 | 2833 | 0.8861 | 0.8753 | MN20160304_L02 | G14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 27.84 | 770.25 | 2497 | 2833 | 0.8811 | 0.8698 | MN20160304_L02 | H15 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 30.06 | 770.25 | 2793 | 3106 | 0.8992 | 0.8971 | MN20160304_L02 | D03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 30.06 | 770.25 | 2828 | 3106 | 0.9105 | 0.9089 | MN20160304_L02 | D05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 30.06 | 770.25 | 2685 | 3106 | 0.8644 | 0.8603 | MN20160304_L02 | G14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 30.06 | 770.25 | 2762 | 3106 | 0.8892 | 0.8866 | MN20160304_L02 | H15 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 32.28 | 770.25 | 3008 | 3392 | 0.8866 | 0.8905 | MN20160304_L02 | D03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 32.28 | 770.25 | 3069 | 3392 | 0.9045 | 0.9084 | MN20160304_L02 | D05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 32.28 | 770.25 | 2901 | 3392 | 0.8550 | 0.8588 | MN20160304_L02 | G14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 32.28 | 770.25 | 2958 | 3392 | 0.8718 | 0.8758 | MN20160304_L02 | H15 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 34.50 | 770.25 | 3314 | 3712 | 0.8928 | 0.9025 | MN20160304_L02 | D03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 34.50 | 770.25 | 3393 | 3712 | 0.9141 | 0.9223 | MN20160304_L02 | D05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 34.50 | 770.25 | 3209 | 3712 | 0.8645 | 0.8757 | MN20160304_L02 | G14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 34.50 | 770.25 | 3259 | 3712 | 0.8780 | 0.8885 | MN20160304_L02 | H15 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 36.73 | 770.25 | 3640 | 4086 | 0.8908 | 0.9062 | MN20160304_L02 | D03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 36.73 | 770.25 | 3751 | 4086 | 0.9180 | 0.9302 | MN20160304_L02 | D05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 36.73 | 770.25 | 3614 | 4086 | 0.8845 | 0.9006 | MN20160304_L02 | G14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 36.73 | 770.25 | 3607 | 4086 | 0.8827 | 0.8990 | MN20160304_L02 | H15 |