LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 76.75 | 770.25 | 79 | 11262 | 0.0070 | -0.4448 | MN20160304_L02 | N09 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 78.98 | 770.25 | 44 | 11518 | 0.0038 | -0.5198 | MN20160304_L02 | K15 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 78.98 | 770.25 | 76 | 11518 | 0.0066 | -0.4476 | MN20160304_L02 | N09 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 81.20 | 770.25 | 50 | 11766 | 0.0042 | -0.5011 | MN20160304_L02 | K15 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 81.20 | 770.25 | 70 | 11766 | 0.0059 | -0.4565 | MN20160304_L02 | N09 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 83.42 | 770.25 | 54 | 12031 | 0.0045 | -0.4884 | MN20160304_L02 | K15 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 83.42 | 770.25 | 81 | 12031 | 0.0067 | -0.4333 | MN20160304_L02 | N09 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 85.64 | 770.25 | 43 | 12287 | 0.0035 | -0.5143 | MN20160304_L02 | K15 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 85.64 | 770.25 | 72 | 12287 | 0.0059 | -0.4474 | MN20160304_L02 | N09 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 87.86 | 770.25 | 49 | 12543 | 0.0039 | -0.4956 | MN20160304_L02 | K15 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 87.86 | 770.25 | 72 | 12543 | 0.0057 | -0.4450 | MN20160304_L02 | N09 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 3.21 | 770.25 | 797 | 904 | 0.8810 | 0.1585 | MN20160304_L02 | D03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 3.21 | 770.25 | 822 | 904 | 0.9087 | 0.3235 | MN20160304_L02 | D05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 3.21 | 770.25 | 758 | 904 | 0.8379 | -0.0668 | MN20160304_L02 | G14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 3.21 | 770.25 | 794 | 904 | 0.8777 | 0.1399 | MN20160304_L02 | H15 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 5.44 | 770.25 | 913 | 1012 | 0.9015 | 0.5381 | MN20160304_L02 | D03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 5.44 | 770.25 | 924 | 1012 | 0.9124 | 0.5855 | MN20160304_L02 | D05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 5.44 | 770.25 | 856 | 1012 | 0.8452 | 0.3065 | MN20160304_L02 | G14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 5.44 | 770.25 | 911 | 1012 | 0.8995 | 0.5296 | MN20160304_L02 | H15 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 7.66 | 770.25 | 1006 | 1090 | 0.9229 | 0.7041 | MN20160304_L02 | D03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 7.66 | 770.25 | 1017 | 1090 | 0.9330 | 0.7415 | MN20160304_L02 | D05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 7.66 | 770.25 | 892 | 1090 | 0.8184 | 0.3404 | MN20160304_L02 | G14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 7.66 | 770.25 | 962 | 1090 | 0.8826 | 0.5586 | MN20160304_L02 | H15 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 10.06 | 770.25 | 1118 | 1218 | 0.9175 | 0.7560 | MN20160304_L02 | D03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 10.06 | 770.25 | 1102 | 1218 | 0.9044 | 0.7182 | MN20160304_L02 | D05 |